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Disseminated Infection Caused by Cunninghamella bertholletiae in a Patient with Beta-Thalassemia
Case Report and Review of the Literature
- JEFF M. SANDS, M.D.;
- ABE M. MACHER, M.D.;
- TIMOTHY J. LEY, M.D.; and
- ARTHUR W. NIENHUIS, M.D.
Abstract
Rare cases of acute mucormycosis in immunocompromised persons have been attributed to Cunninghamella bertholletiae. We report the first known case of this organism causing a chronic, indolent, systemic disease clinically similar to entomophthoramycosis. Cunninghamella bertholletiae is an opportunistic pathogen whose morbidity may be underappreciated because it is usually considered to be a laboratory contaminant.
Article and Author Information
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▸From the Clinical Hematology Branch, National Heart, Lung, and Blood Institute, and the Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Bethesda, Maryland.
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▸Requests for reprints should be addressed to Jeff M. Sands, M.D.; Laboratory of Kidney and Electrolyte Metabolism, Building 10, Room 6N307, National Institutes of Health; Bethesda, MD 20205.
