The Decline in Ischemic Heart Disease Mortality Rates

An Analysis of the Comparative Effects of Medical Interventions and Changes in Lifestyle

  1. LEE GOLDMAN, M.D., M.P.H.; and
  2. E. FRANCIS COOK, ScD.
  1. Boston, Massachusetts

    Abstract

    Using reasonable assumptions gathered from the published literature, we estimated that more than half of the decline in ischemic heart disease mortality between 1968 and 1976 was related to changes in lifestyle, specifically to reductions in serum cholesterol levels and cigarette smoking. In comparison, about 40% of the decline can be directly attributed to specific medical interventions, with coronary care units and the medical treatment of clinical ischemic heart disease and hypertension being the leading estimated contributors. Because many of these interventions have not yet been applied to their maximum potential, a continued decline in mortality rates might be anticipated in the coming decades. However, the relative costs of these medical interventions and lifestyle changes and the extent to which they interact with each other must be considered before an optimal national health strategy can be derived.

    Article and Author Information

    • ▸From the Divisions of Cardiovascular and General Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Boston, Massachusetts.

    • Grant support: in part by a grant from the James Hilton Manning and Emma Austin Manning Foundation, and grant 1 RO1 HS0 4920 from the National Center for Health Services Research. Dr. Goldman is a Henry J. Kaiser Family Foundation Faculty Scholar in General Internal Medicine.

    • ▸Requests for reprints should be addressed to Lee Goldman, M.D.; Department of Medicine, Brigham and Women's Hospital, 75 Francis Street; Boston, MA 02115.

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