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Prednisone Therapy of Post-Transfusion Purpura
- LAURIE J. WEISBERG, M.D.; and
- CHARLES A. LINKER, M.D.
Excerpt
Post-transfusion purpura is a rare syndrome characterized by sudden, severe thrombocytopenia occurring 1 week after a blood transfusion (1). Although most patients have had mild bleeding and recovered spontaneously, some have died from bleeding complications (2). Plasmapheresis and exchange transfusion have resulted in clinical improvement in some cases (3), but other less invasive treatments have failed to produce clear-cut responses (4). We report the case of a patient with post-transfusion purpura in whom prednisone therapy led to a rapid, complete response.
A 59-year-old woman with a history of transfusions and three pregnancies had revision of a hip replacement. There was
This 100-word excerpt has been provided in the absence of an abstract.
Acknowledgments
ACKNOWLEDGMENTS: All HLA studies were done by Dr. Herbert Perkins, Irwin Memorial Blood Bank, San Francisco, California.
Article and Author Information
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▸Requests for reprints should be addressed to Charles A. Linker, M.D.; University of California, San Francisco, 400 Parnassus Avenue A-502; San Francisco, CA 94143.
