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Polymyalgia Rheumatica and Giant Cell Arteritis: First of All, Early Diagnosis!
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Sergio Stagnaro, Reseracher in Biophysical Semeiotics Biophysical Semeiotics Research Laboratory
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dottsergio{at}semeioticabiofisica.it Sergio Stagnaro
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Sirs, as regards the intriguing and fascinating C. Salvarani's et al. article, I agree with its frank conclusion. In addition, as concerns such as rheumatic disorder, a long well-established clinical experience (2-4) allows me to state that first of all we need early bedside diagnosis of both Polymyalgya Rheumatica and most frequently associated Gyant Cell Arteritis (2-4). In my opinion, diagnosing them "two wekks" after their beginn is too later! As a matter of fact, I noticed that cortisone therapy was more successfull, when promptly administered to patients diagnosed in early stage of disorder, recognised clinically with the aid of Biophysical Semeiotics (2-5). Finally, considering the "Variant" Benign Acute Polymyalgya Rheumatica, I described formerly exckusively in individuals, most frequently female, under 60 year-age, involved always by Rheumatic Constitution, conditio sine qua non of disorders, rheumatic in origin (6),soon after flu episode (2, 3), the best therapy proved to be anti-body synthesis stimulation with oral bacterial vaxines. References. 1) Carlo Salvarani, PierLuigi Macchioni, Carlo Manzini,et al.Infliximab plus Prednisone or Placebo plus Prednisone for the Initial Treatment of Polymyalgia Rheumatica: A Randomized Trial. Ann Intern Med 2007; 146: 631 -639. 2)Stagnaro S., Auscultatory Percussion of Rheumatic Diseases. X European Congress of Rheumatology. Moscow. 26 June-July, Proceedings, pg 175. 1983 3) Stagnaro S., Auscultatory Percussion Therapeutic Monitoring and Cerebral Dominance in Rheumatology. 2nd World Congress of Inflammation, Antirheumatics, analgesics, immunomodulators. Abstracts, A. Book 1, pg. 116, March 19-22, Montecarlo 1986 3)Stagnaro S., Polimialgia Reumatica Acuta Benigna Variante. Clin. Ter. 118, 193 [Medline] 4)Stagnaro S., Sindrome percusso-ascoltatoria di Iperfunzione del Sistema Reticolo-Istiocitario. Min. Med. 74, 479, 1983 [Medline] 5) Stagnaro S., Sindrome percusso-ascoltatoria autoimmune. Gazz. Med. It. 142, 555. 1983 6) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico- Biofisiche.Strumento clinico fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine. Travel Factory, Roma, 2004. http://www.travelfactory.it Conflict of Interest:None declared |
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