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Articles: Kay-Tee Khaw, Nicholas Wareham, Sheila Bingham, Robert Luben, Ailsa Welch, and Nicholas Day Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk Ann Intern Med 2004; 141: 413-420 [Abstract] [Full text] [PDF]

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The A1c recommended level should be lowered

John H. Lange   (6 October 2004)

The A1c recommended level should be lowered 6 October 2004
John H. Lange Envirosafe Training and Consultants Send rapid response to journal: Re: The A1c recommended level should be lowered johnhlange{at}worldnet.att.net John H. Lange	Based on the study by Khaw et al (1) there appears to be considerable risk for cardiovascular disease and mortality when the A1c level is 5% or greater. The American Diabetes Association and American Association of Clinical Endocrinologists recommend an A1c goal for diabetics of 7% and 6.5%, respectively (2). Based on Khaw’s study, I suggest that this goal for A1c be lowered to a value of 5%. References 1. Khaw T-T, Wareham N, Bingham S, Luben R, Welch A, Day N. Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk. Ann Intern Med 2004;141:413-20. 2. Palumbo PJ. The case for insulin treatment early in type 2 diabetes. Cleveland Clinic Journal of Medicine 2004;71:385-405. Conflict of Interest: None declared