 |
 |
|
Home |
Current Issue |
Past Issues |
In the Clinic |
ACP Journal Club |
CME |
Collections |
Audio/Video |
Mobile |
Subscribe |
Tools |
Help |
ACP Online
|
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.
SUMMARIES FOR PATIENTS
Coffee Drinkers at Lower Risk for Type 2 Diabetes
6 January 2004 | Volume 140 Issue 1 | Page I-17
Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians.
The summary below is from the full report titled "Coffee Consumption and Risk for Type 2 Diabetes Mellitus." It is in the 6 January 2004 issue of Annals of Internal Medicine (volume 140, pages 1-8). The authors are E. Salazar-Martinez, W.C. Willett, A. Ascherio, J.E. Manson, M.F. Leitzmann, M.J. Stampfer, and F.B. Hu.
What is the problem and what is known about it so far?
Type 2 diabetes mellitus is a common disease that interferes with the body's ability to store energy from food. The pancreas makes insulin, a substance that helps to store energy from food. In people with type 2 diabetes mellitus, the body makes plenty of insulin but cannot use it normally. The result is high blood sugar levels. Over time, high blood sugar levels can lead to blindness, kidney failure, nerve damage, and heart disease. Risk factors for type 2 diabetes mellitus include being overweight, lack of exercise, and family history of the disease. Because type 2 diabetes mellitus is common and has serious complications, it is important to understand factors associated with the disease. It is known that caffeine influences the way the body handles sugar. A recent study in the Netherlands showed that people who drank at least 7 cups of coffee a day were half as likely to develop type 2 diabetes mellitus as people who drank 2 cups or less a day. However, this study did not separate regular from decaffeinated coffee and did not ask the participants about other caffeine-containing drinks.
Why did the researchers do this particular study?
To examine the relationships between type 2 diabetes mellitus and drinking any type of coffee, regular coffee, decaffeinated coffee, and all caffeine-containing drinks.
Who was studied?
41,934 men who had participated in the Health Professionals Follow-up Study and 84,276 women who had participated in the Nurses' Health Study. Participants did not have diabetes, cancer, and heart disease at the start of those large studies of various health issues.
How was the study done?
The men and women in the Health Professionals Follow-up Study and the Nurses' Health Study completed questionnaires every 2 to 4 years that included questions about how frequently they drank coffee and other beverages. The surveys also collected information on health conditions, including type 2 diabetes mellitus. The researchers then compared the frequency with which type 2 diabetes mellitus developed in several groups of people with different intakes of coffee and other caffeine-containing drinks.
What did the researchers find?
While accounting for other diabetes risk factors, such as body size, the researchers found that people who drank more coffee were less likely to develop type 2 diabetes mellitus. This relationship was stronger in women than in men. The researchers did not find a relationship between decaffeinated coffee intake and type 2 diabetes mellitus.
What were the limitations of the study?
The design of this study does not permit the researchers to be certain that coffee decreases incidence of type 2 diabetes mellitus. It might be something else about coffee drinkers that protects them from diabetes.
What are the implications of the study?
This study suggests that further research should examine the influence of caffeine on sugar metabolism.
Related articles in Annals:
This article has been cited by other articles:
|
|
 |
|
  L. A. Bazzano, T. Y. Li, K. J. Joshipura, and F. B. Hu Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women Diabetes Care, July 1, 2008; 31(7): 1311 - 1317. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. L Moisey, S. Kacker, A. C Bickerton, L. E Robinson, and T. E Graham Caffeinated coffee consumption impairs blood glucose homeostasis in response to high and low glycemic index meals in healthy men Am. J. Clinical Nutrition, May 1, 2008; 87(5): 1254 - 1261. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Hayashino, S. Fukuhara, T. Okamura, H. Yamato, H. Tanaka, T. Tanaka, T. Kadowaki, H. Ueshima, and for the HIPOP-OHP Research Group A Prospective Study of Passive Smoking and Risk of Diabetes in a Cohort of Workers: The High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) study Diabetes Care, April 1, 2008; 31(4): 732 - 734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. J. Williams, J. L. Fargnoli, J. J. Hwang, R. M. van Dam, G. L. Blackburn, F. B. Hu, and C. S. Mantzoros Coffee Consumption Is Associated With Higher Plasma Adiponectin Concentrations in Women With or Without Type 2 Diabetes: A prospective cohort study Diabetes Care, March 1, 2008; 31(3): 504 - 507. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Monteiro, A. Farah, D. Perrone, L. C. Trugo, and C. Donangelo Chlorogenic Acid Compounds from Coffee Are Differentially Absorbed and Metabolized in Humans J. Nutr., October 1, 2007; 137(10): 2196 - 2201. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. S. Battram, T. E. Graham, and F. Dela Caffeine's impairment of insulin-mediated glucose disposal cannot be solely attributed to adrenaline in humans J. Physiol., September 15, 2007; 583(3): 1069 - 1077. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Hu, P. Jousilahti, A. Nissinen, S. Bidel, R. Antikainen, and J. Tuomilehto Coffee consumption and the incidence of antihypertensive drug treatment in Finnish men and women Am. J. Clinical Nutrition, August 1, 2007; 86(2): 457 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. S. Uiterwaal, W. M. Verschuren, H B. Bueno-de-Mesquita, M. Ocke, J. M Geleijnse, H. C Boshuizen, P. H. Peeters, E. J. Feskens, and D. E Grobbee Coffee intake and incidence of hypertension Am. J. Clinical Nutrition, March 1, 2007; 85(3): 718 - 723. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Rosner, A. Akesson, M. J. Stampfer, and A. Wolk Coffee Consumption and Risk of Myocardial Infarction among Older Swedish Women Am. J. Epidemiol., February 1, 2007; 165(3): 288 - 293. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Pereira, E. D. Parker, and A. R. Folsom The Potential Benefit of Coffee Consumption--Reply Arch Intern Med, January 22, 2007; 167(2): 205 - 205. [Full Text] [PDF]
|
|
|
|
 |
|
 E. E. Agardh, A. Ahlbom, T. Andersson, and C.-G. Ostenson The magnitude of bias in a cross-sectional study on lifestyle factors in relation to Type 2 diabetes Scand J Public Health, December 1, 2006; 34(6): 665 - 668. [Abstract] [PDF]
|
|
|
|
|
|
N. P. Paynter, H.-C. Yeh, S. Voutilainen, M. I. Schmidt, G. Heiss, A. R. Folsom, F. L. Brancati, and W. H. L. Kao Coffee and Sweetened Beverage Consumption and the Risk of Type 2 Diabetes Mellitus: The Atherosclerosis Risk in Communities Study Am. J. Epidemiol., December 1, 2006; 164(11): 1075 - 1084. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Smith, D. L. Wingard, T. C. Smith, D. Kritz-Silverstein, and E. Barrett-Connor Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose? Diabetes Care, November 1, 2006; 29(11): 2385 - 2390. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. van Dam Green tea, coffee, and diabetes. Ann Intern Med, October 17, 2006; 145(8): 634 - 634. [Full Text] [PDF]
|
|
|
|
|
|
J. A Greenberg, C. N Boozer, and A. Geliebter Coffee, diabetes, and weight control. Am. J. Clinical Nutrition, October 1, 2006; 84(4): 682 - 693. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Pereira, E. D. Parker, and A. R. Folsom Coffee consumption and risk of type 2 diabetes mellitus: an 11-year prospective study of 28 812 postmenopausal women. Arch Intern Med, June 26, 2006; 166(12): 1311 - 1316. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Lopez-Garcia, R. M. van Dam, W. C. Willett, E. B. Rimm, J. E. Manson, M. J. Stampfer, K. M. Rexrode, and F. B. Hu Coffee Consumption and Coronary Heart Disease in Men and Women: A Prospective Cohort Study Circulation, May 2, 2006; 113(17): 2045 - 2053. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. S. Battram, R. Arthur, A. Weekes, and T. E. Graham The Glucose Intolerance Induced by Caffeinated Coffee Ingestion Is Less Pronounced than That Due to Alkaloid Caffeine in Men J. Nutr., May 1, 2006; 136(5): 1276 - 1280. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Iso, C. Date, K. Wakai, M. Fukui, A. Tamakoshi, and and the JACC Study Group* The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults. Ann Intern Med, April 18, 2006; 144(8): 554 - 562. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M Popkin, L. E Armstrong, G. M Bray, B. Caballero, B. Frei, and W. C Willett A new proposed guidance system for beverage consumption in the United States Am. J. Clinical Nutrition, March 1, 2006; 83(3): 529 - 542. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Lopez-Garcia, R. M van Dam, S. Rajpathak, W. C Willett, J. E Manson, and F. B Hu Changes in caffeine intake and long-term weight change in men and women Am. J. Clinical Nutrition, March 1, 2006; 83(3): 674 - 680. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. van Dam, W. C. Willett, J. E. Manson, and F. B. Hu Coffee, Caffeine, and Risk of Type 2 Diabetes: A prospective cohort study in younger and middle-aged U.S. women Diabetes Care, February 1, 2006; 29(2): 398 - 403. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Song, J. E. Manson, J. E. Buring, H. D. Sesso, and S. Liu Associations of Dietary Flavonoids with Risk of Type 2 Diabetes, and Markers of Insulin Resistance and Systemic Inflammation in Women: A Prospective Study and Cross-Sectional Analysis J. Am. Coll. Nutr., October 1, 2005; 24(5): 376 - 384. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B Schulze, K. Hoffmann, J. E Manson, W. C Willett, J. B Meigs, C. Weikert, C. Heidemann, G. A Colditz, and F. B Hu Dietary pattern, inflammation, and incidence of type 2 diabetes in women Am. J. Clinical Nutrition, September 1, 2005; 82(3): 675 - 684. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. S. Schernhammer, F. B. Hu, E. Giovannucci, D. S. Michaud, G. A. Colditz, M. J. Stampfer, and C. S. Fuchs Sugar-Sweetened Soft Drink Consumption and Risk of Pancreatic Cancer in Two Prospective Cohorts Cancer Epidemiol. Biomarkers Prev., September 1, 2005; 14(9): 2098 - 2105. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. van Dam and F. B. Hu Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review JAMA, July 6, 2005; 294(1): 97 - 104. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Wu, W. C. Willett, S. E. Hankinson, and E. Giovannucci Caffeinated Coffee, Decaffeinated Coffee, and Caffeine in Relation to Plasma C-Peptide Levels, a Marker of Insulin Secretion, in U.S. Women Diabetes Care, June 1, 2005; 28(6): 1390 - 1396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Faerch, C. Lau, I. Tetens, O. B. Pedersen, T. Jorgensen, K. Borch-Johnsen, and C. Glumer A Statistical Approach Based on Substitution of Macronutrients Provides Additional Information to Models Analyzing Single Dietary Factors in Relation to Type 2 Diabetes in Danish Adults: the Inter99 Study J. Nutr., May 1, 2005; 135(5): 1177 - 1182. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Lee, R. Hudson, K. Kilpatrick, T. E. Graham, and R. Ross Caffeine Ingestion Is Associated With Reductions in Glucose Uptake Independent of Obesity and Type 2 Diabetes Before and After Exercise Training Diabetes Care, March 1, 2005; 28(3): 566 - 572. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. F Blackburn Issues in reporting epidemiological studies: No data are given to support generalisation BMJ, January 15, 2005; 330(7483): 146 - 146. [Full Text]
|
|
|
|
|
|
E. W. Gregg, B. L. Cadwell, Y. J. Cheng, C. C. Cowie, D. E. Williams, L. Geiss, M. M. Engelgau, and F. Vinicor Trends in the Prevalence and Ratio of Diagnosed to Undiagnosed Diabetes According to Obesity Levels in the U.S. Diabetes Care, December 1, 2004; 27(12): 2806 - 2812. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. van Dam, W. J. Pasman, and P. Verhoef Effects of Coffee Consumption on Fasting Blood Glucose and Insulin Concentrations: Randomized controlled trials in healthy volunteers Diabetes Care, December 1, 2004; 27(12): 2990 - 2992. [Full Text] [PDF]
|
|
|
|
|
|
R. R. Pencek, D. Battram, J. Shearer, F. D. James, D. B. Lacy, K. Jabbour, P. E. Williams, T. E. Graham, and D. H. Wasserman Portal Vein Caffeine Infusion Enhances Net Hepatic Glucose Uptake during a Glucose Load in Conscious Dogs J. Nutr., November 1, 2004; 134(11): 3042 - 3046. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E. Robinson, S. Savani, D. S. Battram, D. H. McLaren, P. Sathasivam, and T. E. Graham Caffeine Ingestion Before an Oral Glucose Tolerance Test Impairs Blood Glucose Management in Men with Type 2 Diabetes J. Nutr., October 1, 2004; 134(10): 2528 - 2533. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. B. Schulze, J. E. Manson, D. S. Ludwig, G. A. Colditz, M. J. Stampfer, W. C. Willett, and F. B. Hu Sugar-Sweetened Beverages, Weight Gain, and Incidence of Type 2 Diabetes in Young and Middle-Aged Women JAMA, August 25, 2004; 292(8): 927 - 934. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. B. Louria Coffee Consumption and Type 2 Diabetes Mellitus Ann Intern Med, August 17, 2004; 141(4): 321 - 321. [Full Text] [PDF]
|
|
|
|
|
|
J. H. Glaser and S. K. Glaser Coffee Consumption and Type 2 Diabetes Mellitus Ann Intern Med, August 17, 2004; 141(4): 323 - 323. [Full Text] [PDF]
|
|
|
|
|
|
B. Schaefer Coffee Consumption and Type 2 Diabetes Mellitus Ann Intern Med, August 17, 2004; 141(4): 321 - 321. [Full Text] [PDF]
|
|
|
|
|
|
F. Soriguer, G. Rojo-Martinez, and I. E. de Antonio Coffee Consumption and Type 2 Diabetes Mellitus Ann Intern Med, August 17, 2004; 141(4): 321 - 323. [Full Text] [PDF]
|
|
|
|
|
|
D. A. Gerber Coffee Consumption and Type 2 Diabetes Mellitus Ann Intern Med, August 17, 2004; 141(4): 323 - 323. [Full Text] [PDF]
|
|
|
|
 |
|
 A. E. Aiello, B. Marshall, S. B. Levy, P. Della-Latta, and E. Larson Relationship between Triclosan and Susceptibilities of Bacteria Isolated from Hands in the Community Antimicrob. Agents Chemother., August 1, 2004; 48(8): 2973 - 2979. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Coffee consumption and risk for type 2 diabetes mellitus Obstet. Gynecol., April 1, 2004; 103(4): 798 - 798. [Full Text] [PDF]
|
|
|
|
|
|
J. Tuomilehto, G. Hu, S. Bidel, J. Lindstrom, and P. Jousilahti Coffee Consumption and Risk of Type 2 Diabetes Mellitus Among Middle-aged Finnish Men and Women JAMA, March 10, 2004; 291(10): 1213 - 1219. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Does Drinking Coffee Decrease Risk for Diabetes? Journal Watch Dermatology, March 3, 2004; 2004(303): 10 - 10. [Full Text]
|
|
|
|
 |
|
 Does Drinking Coffee Decrease Risk for Diabetes? Journal Watch (General), January 30, 2004; 2004(130): 2 - 2. [Full Text]
|
|
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Article
