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Systemic Effects of Nitrofurazone-Impregnated Urinary Catheters in Trauma Patients
Jakob Stensballe, PhD
18 March 2008 | Volume 148 Issue 6 | Page 486
IN RESPONSE:
We thank Dr. Stinnette for his interest. We found no evidence of adverse side effects, such as anemia and liver or respiratory failure, related to the nitrofurazone impregnation of the silicone catheter. This is in accordance with Marion-Landais and colleagues' (1) finding that nitrofurazone is not absorbed to the surrounding tissue or systemically. Furthermore, the observed adverse events in the study were found to be unrelated to the nitrofurazone impregnation and were more likely related to catheterization.
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From Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Potential Financial Conflicts of Interest: Dr. Stensballe is the recipient of an unrestricted research grant from Coloplast A/S.
1. Marion-Landais G, Heotis JP, Mertz JL, Diaz JR, Van Hart DC, Newsom JH, et al. Non-absorption of nitrofurazone from the urethra in men. Curr Ther Res Clin Exp. 1976;19:550-3. [PMID: 820520].[Medline]
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Infection Risk with Nitrofurazone-Impregnated Urinary Catheters in Trauma Patients: A Randomized Trial
Jakob Stensballe, Michael Tvede, Dagnia Looms, Freddy Knudsen Lippert, Benny Dahl, Else Tønnesen, AND Lars Simon Rasmussen
- Annals 2007 147: 285-293.
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