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REPLY
The Diabetes Prevention Program and the Metabolic Syndrome
Trevor J. Orchard, MD;
Marinella Temprosa, MS; and
Robert Ratner, MD
4 October 2005 | Volume 143 Issue 7 | Pages 545-546
IN RESPONSE:
We thank our correspondents for their interesting letters concerning sleep-related breathing disorder and fatty liver as related to the metabolic syndrome. In terms of sleep-related breathing disorder, we unfortunately have no specific data to provide but agree this is an interesting field for future study. We do, however, have data concerning liver enzymes. Although these were not provided in our most recent report because they do not form part of the National Cholesterol Education Program's definition of the metabolic syndrome, we consider this topic so relevant and important that a full, separate paper is in preparation to address the impact on and associations between our interventions and these measures.
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From University of Pittsburgh, Pittsburgh, PA 15213; George Washington University, Rockville, MD 20852; and Medstar Research Institute, Hyattsville, MD 20783.
Potential Financial Conflicts of Interest: None disclosed.
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Articles
The Effect of Metformin and Intensive Lifestyle Intervention on the Metabolic Syndrome: The Diabetes Prevention Program Randomized Trial
Trevor J. Orchard, Marinella Temprosa, Ronald Goldberg, Steven Haffner, Robert Ratner, Santica Marcovina, Sarah Fowler, AND for the Diabetes Prevention Program Research Group
- Annals 2005 142: 611-619.
[ABSTRACT][SUMMARY][Full Text]
