Established in 1927 by the American College of Physicians

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Figure 1. Meta-analysis of total coronary heart disease events. BMD = British Male Doctors' Trial; HOT = Hypertension Optimal Treatment Trial; OR = odds ratio; PHS = Physicians' Health Study; PPP = Primary Prevention Project; TPT = Thrombosis Prevention Trial. The result of the chi-square test for heterogeneity was 8.07 (P = 0.089).

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