 Article
|
|
|
|
Services
|
|
|
|
Google Scholar
|
|
|
|
PubMed
|
|
Articles in PubMed by Author:
|
 |
PubMed
|  |
|
|
REPLY
New Psychopharmacologic Treatment Strategies
Ira D. Glick, MD, and
Charles DeBattista, MD
4 December 2001 | Volume 135 Issue 11 | Page 1008
IN RESPONSE:
We appreciate Dr. Stokes' positive comments about our update. Regarding his concerns, first, we agree that lithium has a "clear early response." Our point was that anticonvulsants, such as divalproex, may allow loading doses to be used, which may allow earlier onset of action (1). Second, although antidepressant effects may be seen in the first week, few clinical trials show a separation from placebo in the first week. Selective serotonin reuptake inhibitors start at full therapeutic dose, but there is likewise little evidence that they separate from placebo in the first week (2).
|
Author and Article Information
|
|---|
Stanford University School of Medicine; Stanford, CA 94305
1. Hirschfeld RM, Allen MH, McEvoy JP, Keck PE Jr, Russell JM. Safety and tolerability of oral loading divalproex sodium in acutely manic bipolar patients J Clin Psychiatry. 1999;60:815-8. [PMID: 10665626].[Medline]
2. Leon AC, Blier P, Culpepper L, Gorman JM, Hirschfeld RM, Nierenberg AA, et al. An ideal trial to test differential onset of antidepressant effect J Clin Psychiatry. 2001;62(Suppl 4):34-6. [PMID: 11229787].
About Letters
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
Related articles in Annals:
-
Updates from the Annual Session
Psychopharmacologic Treatment Strategies for Depression, Bipolar Disorder, and Schizophrenia
Ira D. Glick, Trisha Suppes, Charles DeBattista, Rona J. Hu, AND Stephen Marder
- Annals 2001 134: 47-60.
[ABSTRACT][Full Text]
Top
Author & Article Info
References