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REPLY

Update in Infectious Diseases

right arrow John G. Bartlett, MD

3 July 2001 | Volume 135 Issue 1 | Page 64


IN RESPONSE:

Dr. Lodato makes a good point regarding the contribution of antibiotic abuse in animals to antibiotic resistance and antibiotic-resistant infections in people. Agricultural antibiotic use seems to have been particularly important in vancomycin resistance in Europe (but not the United States), as well as fluoroquinolone resistance in Salmonella species and Campylobacter jejuni. Nevertheless, to keep perspective, the overuse of antibiotics in patients, particularly those with viral respiratory infections, and extensive use of broad-spectrum antibiotics in hospitals probably account for the lion's share of our current dilemma. Having said this, I acknowledge that the publication by Mølbak and colleagues (1) should have made my listing.


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Johns Hopkins University; Baltimore, MD 21287-0003 (Bartlett)


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1. Mølbak K, Baggesen D, Aarestrup F, Ebbesen J, Engberg J, Frydendahl K, et al. An outbreak of multidrug-resistant, quinolone-resistant Salmonella enterica serotype typhimurium DT104 N Engl J Med. 1999;341:1420-5. [PMID: 10547404].[Abstract/Free Full Text]

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Related articles in Annals:

Updates from the Annual Session
Update in Infectious Diseases
John G. Bartlett
Annals 2000 133: 285-292. [Full Text]  

Letters
Update in Infectious Diseases
Robert J. Lodato
Annals 2001 135: 64. [Full Text]  




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