Annals
Established in 1927 by the American College of Physicians
:
Advanced search
 
box Article
 arrow  Table of Contents                
space
box Services
 arrow  Send comment/rapid response letter
space
 arrow  Notify a friend about this article
space
 arrow  Alert me when this article is cited
space
 arrow  Add to Personal Archive
space
 arrow  Download to Citation Manager
space
 arrow  ACP Search                        
space
 arrow  Get Permissions
space
box Google Scholar
 arrow  Search for Related Content
space
box PubMed
Articles in PubMed by Author:
  arrow  Dworkin, M. S.
space
  arrow  Kobayashi, J. M.
space
 arrow  Related Articles in PubMed
space
 arrow  PubMed Citation
space
 arrow  PubMed
space

LETTER

Pertussis in Adults

right arrow Mark S. Dworkin, MD, MPHTM; Christopher Spitters, MD; and John M. Kobayashi, MD, MPH

15 June 1998 | Volume 128 Issue 12 Part 1 | Page 1047


TO THE EDITOR:

Dr. Cherry's editorial [1] was a wake-up call to internists about the importance of pertussis in adults. Pertussis is "highly communicable," and immunity from available vaccines is not long lasting [2]. Outbreaks continue to occur, consuming scarce public health resources [3]. These outbreaks may be exacerbated by physicians' delays in diagnosing the disease in adults. A recent study suggests that internists' knowledge of pertussis is incomplete [4].

We investigated an outbreak of pertussis among 89 office personnel in Washington State. The index case occurred in a 31-year-old woman with paroxysms of coughing, inspiratory whoop, post-tussive vomiting, and serologic evidence of recent infection. We interviewed 61 (68.5%) of 89 employees (including the index case-patient) by using a standardized questionnaire. We defined a clinical case-patient as an employee who had had a cough illness for 2 weeks or longer and at least one of the following symptoms: inspiratory whoop, post-tussive vomiting, or paroxysmal cough. A probable case-patient was defined as an employee who had had a cough illness for at least 2 weeks that occurred during the outbreak period.

Including the index case-patient, we identified 16 case-patients (26%) (7 clinical, 9 probable) with onset within a 4-month period. An inspiratory whoop was present in 3 case-patients (19%); 12 case-patients (75%) stated that they had been vaccinated for pertussis. Although patients were tested late in their illnesses, two of three nasopharyngeal swabs collected from 3 case-patients were positive for Bordetella pertussis by polymerase chain reaction performed in the Pertussis Laboratory at the Centers for Disease Control and Prevention.

This outbreak of pertussis reaffirms the susceptibility of adults to pertussis despite a history of vaccination. We encourage physicians to consult their local public health departments for assistance with testing for B. pertussis when such diagnostic expertise is not readily available at their own medical facilities.


Author and Article Information
space
up arrowTop
dotAuthor & Article Info
down arrowReferences

Centers for Disease Control and Prevention; Atlanta, GA 30333
Snohomish Health District; Everett, WA 98201
Washington State Department of Health; Seattle, WA 98155


References
space
up arrowTop
up arrowAuthor & Article Info
dotReferences

1. Cherry JD. Pertussis in adults [Editorial]. Ann Intern Med. 1998; 128:64-6.

2. Benenson AS, ed. Control of Communicable Diseases Manual. 16th ed. Washington, DC: American Public Health Association; 1995:223-6.

3. Dworkin MS, Alexander ER, Boase JC, et al. Pertussis: What Washington State Health Care Providers Need to Know. Olympia, WA: Washington State Department of Health; 1997.

4. Dworkin MS, Shoemaker P. Pertussis: physician knowledge and practices [Abstract]. Proceedings of the 31st Annual National Immunization Conference, 19-22 May 1997, Detroit, Michigan. Atlanta: Centers for Disease Control and Prevention; 1997.

About Letters
space

The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:

•Include no more than 300 words of text, three authors, and five references

•Type with double-spacing

•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.

Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.

Annals welcomes electronically submitted letters.





box Article
 arrow  Table of Contents                
space
box Services
 arrow  Send comment/rapid response letter
space
 arrow  Notify a friend about this article
space
 arrow  Alert me when this article is cited
space
 arrow  Add to Personal Archive
space
 arrow  Download to Citation Manager
space
 arrow  ACP Search                        
space
 arrow  Get Permissions
space
box Google Scholar
 arrow  Search for Related Content
space
box PubMed
Articles in PubMed by Author:
  arrow  Dworkin, M. S.
space
  arrow  Kobayashi, J. M.
space
 arrow  Related Articles in PubMed
space
 arrow  PubMed Citation
space
 arrow  PubMed
space


 Home | Current Issue | Past Issues | In the Clinic | ACP Journal Club | CME | Collections | Audio/Video | Mobile | Subscribe | Tools | Help | ACP Online