LETTER
Pregnancy-Related Thromboembolism
Arumugam Manoharan, MD
15 July 1997 | Volume 127 Issue 2 | Pages 163-164
TO THE EDITOR:
I read with interest the informative article by Friederich and colleagues [1] and the editorial by Lee [2] on thromboembolic disease and pregnancy. Low-molecular-weight heparin, recommended by Friederich and colleagues and Lee, has been effectively and safely used for thromboprophylaxis during pregnancy [3, 4]. However, no information seems to be available about the drug's safety in relation to breast feeding, and drug companies advise against its use during the puerperium in breast-feeding patients. I would appreciate the authors' comments on this issue.
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Author and Article Information
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St. George Hospital; Kogarah, Sydney, Australia
1. Friederich PW, Sanson BJ, Simioni P, Zanardi S, Huisman MV, Kindt I, et al. Frequency of pregnancy-related venous thromboembolism in anticoagulant factor-deficient women: implications for prophylaxis. Ann Intern Med. 1996; 125:955-60.
2. Lee RV. Thromboembolic disease and pregnancy: are all women equal? [Editorial] Ann Intern Med. 1996; 125:1001-3.
3. Manoharan A. Use of low-molecular weight heparin during pregnancy [Letter]. J Clin Pathol. 1994; 47:94-5.
4. Sturridge F, de Swiet M. The use of low-molecular weight heparin for thromboprophylaxis in pregnancy. Br J Obstet Gynaecol. 1994; 101:69-71.
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