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LETTER

Stuttering Caused by Gabapentin

right arrow Mehran Nissani, MD, and Eduard A. Sanchez, MD

1 March 1997 | Volume 126 Issue 5 | Page 410


TO THE EDITOR:

Gabapentin is an antiepileptic drug that has diverse complications and side effects, but an extensive review of the literature [1] failed to show stuttering as one of the complications [2, 3].

A 58-year-old woman was recently hospitalized because of an intractable seizure. She had been taking Dilantin (Parke Davis, Morris Plains, New Jersey) as an antiepileptic drug. Gabapentin was administered, the seizures stabilized within a few days, and the patient was discharged.

During a follow-up visit in the outpatient clinic, the patient presented with stuttering. The patient denied any history of stuttering. Gabapentin therapy was discontinued; 4 days later, the patient's stuttering subsided.

We believe that this is the first case report to implicate gabapentin as a potential cause of stuttering.


Author and Article Information
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St. John's Episcopal Hospital, Far Rockaway, NY 11691


References
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1. Onslow M. Choosing a treatment procedure for early stuttering: issues and future directions. J Speech Hearing Res. 1992; 35:983-93.

2. Messiha FS. Fluoxentine: adverse effects and drug-drug interactions. J Toxicol Clin Toxicol. 1993; 31:603-30.

3. Watson JB. Improving the effectiveness of stuttering intervention: the journey continues. Folia Phoniatr Logop. 1994; 46:214-22.

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