LETTER
Clinical Use of Apolipoprotein Quantitation
Farooq A. Padder, MD;
Puneet Sahgal, MD; and
Ernesto E. Jonas, MD
1 January 1995 | Volume 122 Issue 1 | Pages 69-70
TO THE EDITOR:
In their excellent review article, Rader and colleagues [1] stated that a 10% decrease in apo B was associated with a 22% increase in coronary artery disease mortality. This result would appear contrary to the expected correlation derived from primary prevention trials such as those of the Lipid Research Clinics [2, 3]. How can this finding be explained?
|
Author and Article Information
|
|---|
Nassau County Medical Center; East Meadow, NY 11554
1. Rader DJ, Hoeg JM, Brewer HB Jr. Quantitation of plasma apolipoproteins in the primary and secondary prevention of coronary artery disease. Ann Intern Med. 1994; 120:1012-25.
2. The Lipid Research Clinics Coronary Primary Prevention Trial results I. Reduction in incidence of coronary heart disease. JAMA. 1984; 251:351-64.
3. The Lipid Research Clinics Coronary Primary Prevention Trial results II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA. 1984; 251:365-74.
About Letters
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
Top
Author & Article Info
References
Article
