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LETTER

Racial Disparities in Coronary Artery Disease Prevalence

right arrow Matthew J. Sorrentino

15 October 1993 | Volume 119 Issue 8 | Page 861


TO THE EDITOR:

Johnson and colleagues [1] speculate that the lower rates of coronary disease in African-Americans compared with whites may be explained by the greater use by African-Americans of emergency departments as primary care facilities. Another explanation is the higher prevalence of hypertension among African-Americans, in that patients with hypertensive heart disease may present with ischemic symptoms but not have significant coronary artery disease.

In our recent study of consecutive African-American and white patients referred for coronary angiography [2], we also found a lower prevalence of coronary artery disease among African-Americans than among whites (71% compared with 84%, P < 0.05). African-American patients, however, had significantly more hypertension (78% compared with 52%, P < 0.05) and diabetes mellitus (36% compared with 23%, P < 0.05) than did white patients. In contrast to the present study, the degree of coronary artery disease as assessed by a coronary artery disease score was the same for the two races. Presenting symptoms can be unreliable in determining underlying disease [3]. Data on coexisting disease in the study by Johnson and associates may explain why African-American patients presenting with acute chest pain seem to have a lower prevalence of coronary artery disease.


References
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1. Johnson PA, Lee TH, Cook EF, Rouan GW, Goldman L. Effect of race on the presentation and management of patients with acute chest pain. Ann Intern Med. 1993; 118:593-601.

2. Sorrentino MJ, Vielhauer C, Eisenbart JD, Fless GM, Scanu AM, Feldman T. Plasma lipoprotein(a) protein concentration and coronary artery disease in black patients compared with white patients. Am J Med. 1992; 93:658-62.

3. Sorrentino MJ, Feldman T. Clinical and electrocardiographic limitations on the diagnosis of acute myocardial infarction: Implications for thrombolytic therapy. J Invasive Cardiol. 1990; 2:187-92.

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