REPLY
Angiotensin-converting-Enzyme Inhibitors and Chyluria
Taha Keilani;
William Schlueter; and
Daniel Batlle
15 December 1993 | Volume 119 Issue 12 | Pages 1223-1224
IN RESPONSE:
We found Dr. Saleh's observation and comments interesting. The reduction of chyluria with an ACE inhibitor is indeed a novel observation that will require confirmation by prospective studies. If confirmed, the mechanism could be a hemodynamic effect on the lymphatic circulation, resulting in reduction of chyluria. We are aware of one report claiming that an ACE inhibitor reduced the amount of protein lost across the peritoneal membrane in patients undergoing peritoneal dialysis [1]. A link could exist between these isolated observations.
1. Coronel F, Hortal L, Naranjo P, Cruceyra A, Barrientos A. Captopril, proteinuria and peritoneal protein leakage in diabetic patients (Letter). Nephron. 1989; 51:443.
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