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Screening Primary Care Patients for Hereditary Hemochromatosis with Transferrin Saturation and Serum Ferritin Level: Systematic Review for the American College of Physicians


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  		Table 1. Prevalence of Hereditary Hemochromatosis in Primary Care Settings

 

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  		Table 2. Prevalence of Hereditary Hemochromatosis in Various General Population Settings

 

Figure 1
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  		Appendix Figure 1. The selection and exclusion of articles to address subquestion 1 about the prevalence of hereditary hemochromatosis.{webonly}

 

Figure 2
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  		Appendix Figure 2. The selection and exclusion of articles to address subquestion 2 about the magnitude of complications with primary iron overload (biochemical measures).{webonly}

 

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  		Table 3. Longitudinal Studies of Primary Iron Overload and Overt Hemochromatosis or Complications

 

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  		Table 4. Relationship between Primary Iron Overload Defined by Transferrin Saturation and Serum Ferritin Level and Diabetes Mellitus

 

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  		Table 5. Relationship between Primary Iron Overload Defined by Transferrin Saturation or Serum Ferritin Level and Cirrhosis

 

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  		Table 6. Relationship between Primary Iron Overload Defined by Transferrin Saturation or Serum Ferritin Level and Cardiomyopathy or Mortality

 

Figure 3
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  		Appendix Figure 3. The selection and exclusion of articles to address subquestion 2 about the magnitude of complications with primary iron overloading (iron deposition).{webonly}

 

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  		Table 7. Relationship between Primary Iron Overload Defined by Tissue Iron Deposition and Complications

 

Figure 4
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  		Appendix Figure 4. The selection and exclusion of articles to address subquestion 3 about the diagnostic usefulness of transferrin saturation and serum ferritin level.{webonly}

 

Figure 5
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  		Appendix Figure 5. The selection and exclusion of articles to address subquestion 4 about the treatment of hereditary hemochromatosis.{webonly}

 



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