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PowerPoint slides are available for most Figures at Annals.org

Systematic Review: Comparative Effectiveness and Harms of Treatments for Clinically Localized Prostate Cancer


Figure 1
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  		Appendix Figure 1. Study flow diagram.{webonly}

AUA = American Urological Association.

 

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  		Table 1. Summary of Evidence on the Comparative Effectiveness and Harms of Therapies for Localized Prostate Cancer*

 

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  		Figure 1. Overall survival at time points by treatment from nonrandomized studies.

Brachy = brachytherapy; C-EBRT = conformal external-beam radiation therapy, EBRT = external-beam radiation therapy; RP = radical prostatectomy; WW = watchful waiting.

 

Figure 2
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  		Figure 2. Complications of brachytherapy, radical prostatectomy, external beam radiation therapy, conformal radiation therapy, nerve sparing radical prostatectomy and watchful waiting from nonrandomized studies.

The point size is proportional to the number of patients: <50, 50 to 150, 150 to 300, or >300. EBRT = external-beam radiation therapy.

 

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  		Appendix Table 1. Description and Quality of the Included Randomized Trials*{webonly}

 

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  		Table 2. All-Cause Mortality in Randomized, Controlled Trials*

 

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  		Appendix Table 2. Biochemical or Clinical Progression or Recurrence in Randomized, Controlled Trials from the Era of Prostate-Specific Antigen Testing*{webonly}

 

Figure 2
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  		Appendix Figure 2. Biochemical progression–free survival after cryotherapy or high-intensity focused ultrasonography among patients in nonrandomized clinical trials and case series.{webonly}

*Combined with transurethral resection of the prostate.

 

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  		Appendix Figure 3. Clinical outcomes after laparoscopic radical prostatectomy, robotic-assisted radical prostatectomy, or intensity-modulated radiation therapy.{webonly}

PSA = prostate-specific antigen.

 

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  		Appendix Table 3. Patient Characteristics and Response to Therapy at 24 Months of Follow-up, by Treatment in the Prostate Cancer Outcomes Study*{webonly}

 



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