Home |
Current Issue |
Past Issues |
In the Clinic |
ACP Journal Club |
CME |
Collections |
Audio/Video |
Mobile |
Subscribe |
Tools |
Help |
ACP Online
|
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 June 1999 | Volume 130 Issue 11 | Pages 910-921
The term functional somatic syndrome has been applied to several related syndromes characterized more by symptoms, suffering, and disability than by consistently demonstrable tissue abnormality. These syndromes include multiple chemical sensitivity, the sick building syndrome, repetition stress injury, the side effects of silicone breast implants, the Gulf War syndrome, chronic whiplash, the chronic fatigue syndrome, the irritable bowel syndrome, and fibromyalgia. Patients with functional somatic syndromes have explicit and highly elaborated self-diagnoses, and their symptoms are often refractory to reassurance, explanation, and standard treatment of symptoms. They share similar phenomenologies, high rates of co-occurrence, similar epidemiologic characteristics, and higher-than-expected prevalences of psychiatric comorbidity. Although discrete pathophysiologic causes may ultimately be found in some patients with functional somatic syndromes, the suffering of these patients is exacerbated by a self-perpetuating, self-validating cycle in which common, endemic, somatic symptoms are incorrectly attributed to serious abnormality, reinforcing the patient's belief that he or she has a serious disease. Four psychosocial factors propel this cycle of symptom amplification: the belief that one has a serious disease; the expectation that one's condition is likely to worsen; the "sick role," including the effects of litigation and compensation; and the alarming portrayal of the condition as catastrophic and disabling. The climate surrounding functional somatic syndromes includes sensationalized media coverage, profound suspicion of medical expertise and physicians, the mobilization of parties with a vested self-interest in the status of functional somatic syndromes, litigation, and a clinical approach that overemphasizes the biomedical and ignores psychosocial factors. All of these influences exacerbate and perpetuate the somatic distress of patients with functional somatic syndromes, heighten their fears and pessimistic expectations, prolong their disability, and reinforce their sick role. A six-step strategy for helping patients with functional somatic syndromes is presented here.
Author and Article Information
From Brigham and Women's Hospital, Boston, Massachusetts.
Acknowledgments: The authors thank Thomas Delbanco, MD, George E. Vaillant, MD, and Leon Eisenberg, MD, for assistance in preparing this manuscript.
Grant Support: In part by research grant MH-40487 from the National Institute of Mental Health (Bethesda, Maryland).
Requests for Reprints: Arthur J. Barsky, MD, Division of Psychiatry, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.
Current Author Addresses: Drs. Barsky and Borus: Division of Psychiatry, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115. REVIEW
Functional Somatic Syndromes
![]()
Related articles in Annals:
This article has been cited by other articles:
![]() |
D. S. Ciccone, L. Weissman, and B. H. Natelson Chronic Fatigue Syndrome in Male Gulf War Veterans and Civilians: A Further Test of the Single Syndrome Hypothesis J Health Psychol, May 1, 2008; 13(4): 529 - 536. [Abstract] [PDF] |
||||
![]() |
S. B. Harvey, M. Wadsworth, S. Wessely, and M. Hotopf Etiology of Chronic Fatigue Syndrome: Testing Popular Hypotheses Using a National Birth Cohort Study Psychosom Med, May 1, 2008; 70(4): 488 - 495. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. W. Hoge, D. McGurk, J. L. Thomas, A. L. Cox, C. C. Engel, and C. A. Castro Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq N. Engl. J. Med., January 31, 2008; 358(5): 453 - 463. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. A. A. Kanaan, J. P. Lepine, and S. C. Wessely The Association or Otherwise of the Functional Somatic Syndromes Psychosom Med, November 1, 2007; 69(9): 855 - 859. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Salmon, G. M. Humphris, A. Ring, J. C. Davies, and C. F. Dowrick Primary Care Consultations About Medically Unexplained Symptoms: Patient Presentations and Doctor Responses That Influence the Probability of Somatic Intervention Psychosom Med, July 1, 2007; 69(6): 571 - 577. [Abstract] [Full Text] [PDF] |
||||
![]() |
A.E. Vertigan, D.G. Theodoros, P.G. Gibson, and A.L. Winkworth REVIEW SERIES: Chronic cough: Behaviour modification therapies for chronic cough Chronic Respiratory Disease, May 1, 2007; 4(2): 89 - 97. [Abstract] [PDF] |
||||
![]() |
M. P. Jones, M. D. Crowell, K. W. Olden, and F. Creed Functional Gastrointestinal Disorders: An Update for the Psychiatrist Psychosomatics, April 1, 2007; 48(2): 93 - 102. [Abstract] [Full Text] [PDF] |
||||
![]() |
K Osterberg, R Persson, B Karlson, F C. Eek, and P Orbaek Personality, mental distress, and subjective health complaints among persons with environmental annoyance Human and Experimental Toxicology, March 1, 2007; 26(3): 231 - 241. [Abstract] [PDF] |
||||
![]() |
K. Kanbara, M. Fukunaga, H. Mutsuura, H. Takeuchi, K. Kitamura, and Y. Nakai An Exploratory Study of Subgrouping of Patients With Functional Somatic Syndrome Based on the Psychophysiological Stress Response: Its Relationship With Moods and Subjective Variables Psychosom Med, February 1, 2007; 69(2): 158 - 165. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Sperry Utilizing a Family-Sensitive Cognitive Behavioral Intervention With Chronic Illness: The Impact of Family Dynamics and Therapy on Medical Symptoms The Family Journal, January 1, 2007; 15(1): 56 - 61. [Abstract] [PDF] |
||||
![]() |
P. Fink, T. Toft, M. S. Hansen, E. Ornbol, and F. Olesen Symptoms and Syndromes of Bodily Distress: An Exploratory Study of 978 Internal Medical, Neurological, and Primary Care Patients Psychosom Med, January 1, 2007; 69(1): 30 - 39. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Cardol, W. J.H.M. van den Bosch, P. Spreeuwenberg, P. P. Groenewegen, L. van Dijk, and D. H. de Bakker All in the Family: Headaches and Abdominal Pain as Indicators for Consultation Patterns in Families Ann. Fam. Med, November 1, 2006; 4(6): 506 - 511. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Waddell Preventing incapacity in people with musculoskeletal disorders Br. Med. Bull., October 5, 2006; (2006) ldl008v2. [Abstract] [Full Text] [PDF] |
||||
![]() |
A C Huizink, P Slottje, A B Witteveen, J A Bijlsma, J W R Twisk, N Smidt, I Bramsen, W van Mechelen, H M van der Ploeg, L M Bouter, et al. Long term health complaints following the Amsterdam Air Disaster in police officers and fire-fighters Occup. Environ. Med., October 1, 2006; 63(10): 657 - 662. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. E. Locke Presidential address: psychosomatic medicine and biodefense preparedness--a new role for the american psychosomatic society. Psychosom Med, September 1, 2006; 68(5): 698 - 705. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Salmon, G. M. Humphris, A. Ring, J. C. Davies, and C. F. Dowrick Why Do Primary Care Physicians Propose Medical Care to Patients With Medically Unexplained Symptoms? A New Method of Sequence Analysis to Test Theories of Patient Pressure Psychosom Med, July 1, 2006; 68(4): 570 - 577. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. van Kamp, P. G. van der Velden, R. K. Stellato, J. Roorda, J. van Loon, R. J. Kleber, B. B. R. Gersons, and E. Lebret Physical and mental health shortly after a disaster: first results from the Enschede firework disaster study Eur J Public Health, June 1, 2006; 16(3): 252 - 258. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. J H Soeteman, C J. Yzermans, J. J Kerssens, A. J E Dirkzwager, G. A Donker, W. J H M van den Bosch, and J. van der Zee The course of post-disaster health problems of victims with pre-disaster psychological problems as presented in general practice Fam. Pract., June 1, 2006; 23(3): 378 - 384. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Moss-Morris and M. Spence To "Lump" or to "Split" the Functional Somatic Syndromes: Can Infectious and Emotional Risk Factors Differentiate Between the Onset of Chronic Fatigue Syndrome and Irritable Bowel Syndrome? Psychosom Med, May 1, 2006; 68(3): 463 - 469. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Wade Why physical medicine, physical disability and physical rehabilitation? We should abandon Cartesian dualism Clinical Rehabilitation, March 1, 2006; 20(3): 185 - 190. [Abstract] [PDF] |
||||
![]() |
C. Ryall, D. Coggon, R. Peveler, I. Reading, and K. T. Palmer A case-control study of risk factors for arm pain presenting to primary care services Occup. Med., March 1, 2006; 56(2): 137 - 143. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Turner Factitious Disorders: Reformulating the DSM-IV Criteria Psychosomatics, February 1, 2006; 47(1): 23 - 32. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. D Shapiro, R. Dattwyler, R. B Nadelman, and G. P Wormser Response to meta-analysis of Lyme borreliosis symptoms Int. J. Epidemiol., December 1, 2005; 34(6): 1437 - 1439. [Full Text] [PDF] |
||||
![]() |
P. Slottje, J. A. Bijlsma, N. Smidt, J. W. R. Twisk, A. C. Huizink, W. F. Lems, I. van Hoogstraten, A. B. Witteveen, W. van Mechelen, and T. Smid Epidemiologic Study of the Autoimmune Health Effects of a Cargo Aircraft Disaster Arch Intern Med, October 24, 2005; 165(19): 2278 - 2285. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Loder and D. Biondi Headache Attributed to Psychiatric Disorder: A Case Series Psychosomatics, August 1, 2005; 46(4): 326 - 333. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. T Hamilton, A. M Gallagher, J. M Thomas, and P. D White The prognosis of different fatigue diagnostic labels: a longitudinal survey Fam. Pract., August 1, 2005; 22(4): 383 - 388. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. van den Berg, L. Grievink, J. Yzermans, and E. Lebret Medically Unexplained Physical Symptoms in the Aftermath of Disasters Epidemiol. Rev., July 1, 2005; 27(1): 92 - 106. [Full Text] [PDF] |
||||
![]() |
P. Vasterman, C. J. Yzermans, and A. J. E. Dirkzwager The Role of the Media and Media Hypes in the Aftermath of Disasters Epidemiol. Rev., July 1, 2005; 27(1): 107 - 114. [Full Text] [PDF] |
||||
![]() |
F. Creed, E. Guthrie, J. Ratcliffe, L. Fernandes, C. Rigby, B. Tomenson, N. Read, and D. G. Thompson Reported Sexual Abuse Predicts Impaired Functioning but a Good Response to Psychological Treatments in Patients With Severe Irritable Bowel Syndrome Psychosom Med, May 1, 2005; 67(3): 490 - 499. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. J.H. Deeg, A. C. Huizink, H. C. Comijs, and T. Smid Disaster and associated changes in physical and mental health in older residents Eur J Public Health, April 1, 2005; 15(2): 170 - 174. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. H. Natelson, S. A. Weaver, C.-L. Tseng, and J. E. Ottenweller Spinal Fluid Abnormalities in Patients with Chronic Fatigue Syndrome Clin. Vaccine Immunol., January 1, 2005; 12(1): 52 - 55. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. T Wade and P. W Halligan Do biomedical models of illness make for good healthcare systems? BMJ, December 11, 2004; 329(7479): 1398 - 1401. [Full Text] [PDF] |
||||
![]() |
J Roorda, W A H J van Stiphout, and R R R Huijsman-Rubingh Post-disaster health effects: strategies for investigation and data collection. Experiences from the Enschede firework disaster J. Epidemiol. Community Health, December 1, 2004; 58(12): 982 - 987. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A. Mainster, B. E. Stuck, and J. Brown Jr Assessment of Alleged Retinal Laser Injuries Arch Ophthalmol, August 1, 2004; 122(8): 1210 - 1217. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Ranjith and R. Mohan Dhat syndrome: a functional somatic syndrome? The British Journal of Psychiatry, July 1, 2004; 185(1): 77 - 77. [Full Text] [PDF] |
||||
![]() |
S. Tan, K. Tillisch, and E. Mayer Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine Evid. Based Complement. Altern. Med., June 1, 2004; 1(1): 35 - 40. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Hinton, V. Pich, D. Chhean, and M. Pollack Olfactory-Triggered Panic Attacks among Khmer Refugees: A Contextual Approach Transcultural Psychiatry, June 1, 2004; 41(2): 155 - 199. [Abstract] [PDF] |
||||
![]() |
C. G. Kooiman, J. H. Bolk, H. G. M. Rooijmans, and R. W. Trijsburg Alexithymia Does Not Predict the Persistence of Medically Unexplained Physical Symptoms Psychosom Med, March 1, 2004; 66(2): 224 - 232. [Abstract] [Full Text] [PDF] |
||||
![]() |
C Cedraschi, J Desmeules, E Rapiti, E Baumgartner, P Cohen, A Finckh, A F Allaz, and T L Vischer Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management Ann Rheum Dis, March 1, 2004; 63(3): 290 - 296. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. L. Dobkin, M. De Civita, S. Bernatsky, H. Kang, and M. Baron Does psychological vulnerability determine health-care utilization in fibromyalgia? Rheumatology, November 1, 2003; 42(11): 1324 - 1331. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Salmon, S. M. Al-Marzooqi, G. Baker, and J. Reilly Childhood Family Dysfunction and Associated Abuse in Patients With Nonepileptic Seizures: Towards a Causal Model Psychosom Med, July 1, 2003; 65(4): 695 - 700. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. S. Smith, S. P. Martin-Herz, W. M. Womack, and J. L. Marsigan Comparative Study of Anxiety, Depression, Somatization, Functional Disability, and Illness Attribution in Adolescents With Chronic Fatigue or Migraine Pediatrics, April 1, 2003; 111(4): e376 - 381. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Hazemeijer and J. J. Rasker Fibromyalgia and the therapeutic domain. A philosophical study on the origins of fibromyalgia in a specific social setting Rheumatology, April 1, 2003; 42(4): 507 - 515. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. S. Ciccone and B. H. Natelson Comorbid Illness in Women With Chronic Fatigue Syndrome: A Test of the Single Syndrome Hypothesis Psychosom Med, March 1, 2003; 65(2): 268 - 275. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. M. Kuhn and M. A. Ghannoum Indoor Mold, Toxigenic Fungi, and Stachybotrys chartarum: Infectious Disease Perspective Clin. Microbiol. Rev., January 1, 2003; 16(1): 144 - 172. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. R. Gold, F. Dipalo, M. S. Gold, and D. O'Hearn The Symptoms and Signs of Upper Airway Resistance Syndrome: A Link to the Functional Somatic Syndromes Chest, January 1, 2003; 123(1): 87 - 95. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Peters, I. Stanley, M. Rose, S. Kaney, and P. Salmon A randomized controlled trial of group aerobic exercise in primary care patients with persistent, unexplained physical symptoms Fam. Pract., December 1, 2002; 19(6): 665 - 674. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. A. Allen, J. I. Escobar, P. M. Lehrer, M. A. Gara, and R. L. Woolfolk Psychosocial Treatments for Multiple Unexplained Physical Symptoms: A Review of the Literature Psychosom Med, November 1, 2002; 64(6): 939 - 950. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. P. BENTALL, P. POWELL, F. J. NYE, and R. H. T. EDWARDS Predictors of response to treatment for chronic fatigue syndrome The British Journal of Psychiatry, September 1, 2002; 181(3): 248 - 252. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. S. Ciechanowski, W. J. Katon, J. E. Russo, and M. M. Dwight-Johnson Association of Attachment Style to Lifetime Medically Unexplained Symptoms in Patients With Hepatitis C Psychosomatics, June 1, 2002; 43(3): 206 - 212. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. C. Gray, R. J. Reed, K. S. Kaiser, T. C. Smith, and V. M. Gastanaga Self-reported Symptoms and Medical Conditions among 11,868 Gulf War-era Veterans : The Seabee Health Study Am. J. Epidemiol., June 1, 2002; 155(11): 1033 - 1044. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. E. BARTHOLOMEW and S. WESSELY Protean nature of mass sociogenic illness: From possessed nuns to chemical and biological terrorism fears The British Journal of Psychiatry, April 1, 2002; 180(4): 300 - 306. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. B. Nadelman and G. P. Wormser Recognition and Treatment of Erythema Migrans: Are We Off Target? Ann Intern Med, March 19, 2002; 136(6): 477 - 479. [Full Text] [PDF] |
||||
![]() |
A. J. Barsky, R. Saintfort, M. P. Rogers, and J. F. Borus Nonspecific Medication Side Effects and the Nocebo Phenomenon JAMA, February 6, 2002; 287(5): 622 - 627. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. V. Campo and G. Fritz A Management Model for Pediatric Somatization Psychosomatics, December 1, 2001; 42(6): 467 - 476. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. H. Lavietes, J. Matta, L. A. Tiersky, B. H. Natelson, L. Bielory, and N. S. Cherniack The Perception of Dyspnea in Patients With Mild Asthma Chest, August 1, 2001; 120(2): 409 - 415. [Abstract] [Full Text] [PDF] |
||||
![]() |
D M Dush Breast implants and illness: a model of psychological factors Ann Rheum Dis, July 1, 2001; 60(7): 653 - 657. [Abstract] [Full Text] [PDF] |
||||
![]() |
|