Annals
Established in 1927 by the American College of Physicians
:
Advanced search
 
box Article
 arrow  Table of Contents                
space
 arrow  Full Text of this article Free
space
 arrow  Figures/Tables List
space
box Services
 arrow  Send comment/rapid response letter
space
 arrow  Notify a friend about this article
space
 arrow  Alert me when this article is cited
space
 arrow  Add to Personal Archive
space
 arrow  Download to Citation Manager
space
 arrow  ACP Search                        
space
 arrow  Get Permissions
space
box Google Scholar
 arrow  Search for Related Content
space
box PubMed
Articles in PubMed by Author:
  arrow  Hakim, R. B.
space
 arrow  Related Articles in PubMed
space
 arrow  PubMed Citation
space
 arrow  PubMed
space

ARTICLE

Factors Associated with Do-Not-Resuscitate Orders: Patients' Preferences, Prognoses, and Physicians' Judgments

right arrow Rosemarie B. Hakim, PhD; Joan M. Teno, MD; Frank E. Harrell Jr., PhD; William A. Knaus, MD; Neil Wenger, MD; Russell S. Phillips, MD; Peter Layde, MD; Robert Califf, MD; Alfred F. Connors Jr., MD; Joanne Lynn, MD, for the SUPPORT Investigators*

15 August 1996 | Volume 125 Issue 4 | Pages 284-293

Background: Medical treatment decisions should be based on the preferences of informed patients or their proxies and on the expected outcomes of treatment. Because seriously ill patients are at risk for cardiac arrest, examination of do-not-resuscitate (DNR) practices affecting them provides useful insights into the associations between various factors and medical decision making.

Objective: To examine the association between patients' preferences for resuscitation (along with other patient and physician characteristics) and the frequency and timing of DNR orders.

Design: Prospective cohort study.

Setting: 5 teaching hospitals.

Patients: 6802 seriously ill hospitalized patients enrolled in the Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment (SUPPORT) between 1989 and 1994.

Measurements: Patients and their surrogates were interviewed about patients' cardiopulmonary resuscitation preferences, medical records were reviewed to determine disease severity, and a multivariable regression model was constructed to predict the time to the first DNR order.

Results: The patients' preference for cardiopulmonary resuscitation was the most important predictor of the timing of DNR orders, but only 52% of patients who preferred not to be resuscitated actually had DNR orders written. The probability of surviving for 2 months was the next most important predictor of the timing of DNR orders. Although DNR orders were not linearly related to the probability of surviving for 2 months, they were written earlier and more frequently for patients with a 50% or lower probability of surviving for 2 months. Orders were written more quickly for patients older than 75 years of age, regardless of prognosis. After adjustment for these and other influential patient characteristics, the use and timing of DNR orders varied significantly among physician specialties and among hospitals.

Conclusions: Patients' preferences and short-term prognoses are associated with the timing of DNR orders. However, the substantial variation seen among hospital sites and among physician specialties suggests that there is room for improvement. In this study, DNR orders were written earlier for patients older than 75 years of age, regardless of prognosis. This finding suggests that physicians may be using age in a way that is inconsistent with the reported association between age and survival. The process for making decisions about DNR orders needs to be improved if such orders are to routinely and accurately reflect patients' preferences and probable outcomes.

*For a list of the SUPPORT investigators, see the Appendix.

Author and Article Information
space

From George Washington University Medical Center, Washington, D.C.; Duke University Medical Center, Durham, North Carolina; University of Los Angeles, Los Angeles, California; Beth Israel Hospital, Boston, Massachusetts; Medical College of Wisconsin, Milwaukee, Wisconsin; Marshfield Clinic, Marshfield, Wisconsin; and MetroHealth Medical Center, Cleveland, Ohio.
Grant Support: By the Robert Wood Johnson Foundation.
Requests for Reprints: Joan M. Teno, MD, MS, Center to Improve Care of the Dying, George Washington Medical Center, 1001 22nd Street, Suite 820, Washington, DC 20037.
Current Author Addresses: Dr. Hakim: The Health Care Financing Administration, 7850 Security Boulevard, Baltimore, MD 21244. Drs. Teno and Lynn: Center to Improve Care of the Dying, George Washington Medical Center, 1001 22nd Street, Suite 820, Washington, DC 20037.




This article has been cited by other articles:


Home page
J. Med. EthicsHome page
E D Morrell, B P Brown, R Qi, K Drabiak, and P R Helft
The do-not-resuscitate order: associations with advance directives, physician specialty and documentation of discussion 15 years after the Patient Self-Determination Act
J. Med. Ethics, September 1, 2008; 34(9): 642 - 647.
[Abstract] [Full Text] [PDF]


Home page
J. Med. EthicsHome page
D P Sulmasy, J R Sood, and W A Ury
Physicians' confidence in discussing do not resuscitate orders with patients and surrogates
J. Med. Ethics, February 1, 2008; 34(2): 96 - 101.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
S. Varma and D. Wendler
Medical Decision Making for Patients Without Surrogates
Arch Intern Med, September 10, 2007; 167(16): 1711 - 1715.
[Abstract] [Full Text] [PDF]


Home page
NeurologyHome page
D. B. Zahuranec, D. L. Brown, L. D. Lisabeth, N. R. Gonzales, P. J. Longwell, M. A. Smith, N. M. Garcia, and L. B. Morgenstern
Early care limitations independently predict mortality after intracerebral hemorrhage
Neurology, May 15, 2007; 68(20): 1651 - 1657.
[Abstract] [Full Text] [PDF]


Home page
J Intensive Care MedHome page
A. A. El Solh and F. H. Ramadan
Overview of Respiratory Failure in Older Adults
J Intensive Care Med, December 1, 2006; 21(6): 345 - 351.
[Abstract] [PDF]


Home page
Am J Crit CareHome page
D. A. Gruenberg, W. Shelton, S. L. Rose, A. E. Rutter, S. Socaris, and G. McGee
Factors influencing length of stay in the intensive care unit.
Am. J. Crit. Care., September 1, 2006; 15(5): 502 - 509.
[Abstract] [Full Text] [PDF]


Home page
Age AgeingHome page
J. S. Balami, S. M. Packham, and M. A. Gosney
Non-invasive ventilation for respiratory failure due to acute exacerbations of chronic obstructive pulmonary disease in older patients
Age Ageing, January 1, 2006; 35(1): 75 - 79.
[Full Text] [PDF]


Home page
NEJMHome page
D. Casarett, J. Kapo, and A. Caplan
Appropriate Use of Artificial Nutrition and Hydration -- Fundamental Principles and Recommendations
N. Engl. J. Med., December 15, 2005; 353(24): 2607 - 2612.
[Full Text] [PDF]


Home page
ChestHome page
M. M. LeClaire, J. M. Oakes, and C. R. Weinert
Communication of Prognostic Information for Critically Ill Patients
Chest, September 1, 2005; 128(3): 1728 - 1735.
[Abstract] [Full Text] [PDF]


Home page
Postgrad. Med. J.Home page
C A Marco
Ethical issues of resuscitation: an American perspective
Postgrad. Med. J., September 1, 2005; 81(959): 608 - 612.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
D. S. Zingmond and N. S. Wenger
Regional and Institutional Variation in the Initiation of Early Do-Not-Resuscitate Orders
Arch Intern Med, August 8, 2005; 165(15): 1705 - 1712.
[Abstract] [Full Text] [PDF]


Home page
AM J HOSP PALLIAT CAREHome page
C. A. Marco, N. Buderer, and D. Thum Sr.
End-of-life care: Perspectives of family members of deceased patients
American Journal of Hospice and Palliative Medicine, January 1, 2005; 22(1): 26 - 31.
[Abstract] [PDF]


Home page
Canadian J. AnesthesiaHome page
T. Sinuff, D. J. Cook, G. M. Rocker, L. E. Griffith, S. D. Walter, M. M. Fisher, P. M. Dodek, P. Sjokvist, E. McDonald, J. C. Marshall, et al.
DNR directives are established early in mechanically ventilated intensive care unit patients: [Les directives PDR sont etablies tot chez les patients sous ventilation mecanique a l'unite des soins intensifs]
Can J Anesth, December 1, 2004; 51(10): 1034 - 1041.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
E. A. Jackson, J. L. Yarzebski, R. J. Goldberg, B. Wheeler, J. H. Gurwitz, D. M. Lessard, S. E. Bedell, and J. M. Gore
Do-Not-Resuscitate Orders in Patients Hospitalized With Acute Myocardial Infarction: The Worcester Heart Attack Study
Arch Intern Med, April 12, 2004; 164(7): 776 - 783.
[Abstract] [Full Text] [PDF]


Home page
J. Med. EthicsHome page
E P Cherniack
Increasing use of DNR orders in the elderly worldwide: whose choice is it?
J. Med. Ethics, October 1, 2002; 28(5): 303 - 307.
[Abstract] [Full Text] [PDF]


Home page
GerontologistHome page
J. C. Hays, A. N. Galanos, T. A. Palmer, D. R. McQuoid, and E. P. Flint
Preference for Place of Death in a Continuing Care Retirement Community
Gerontologist, February 1, 2001; 41(1): 123 - 128.
[Abstract] [Full Text]


Home page
JAMAHome page
S. J. Goodlin, Z. Zhong, J. Lynn, J. M. Teno, J. P. Fago, N. Desbiens, A. F. Connors Jr, N. S. Wenger, and R. S. Phillips
Factors Associated With Use of Cardiopulmonary Resuscitation in Seriously Ill Hospitalized Adults
JAMA, December 22, 1999; 282(24): 2333 - 2339.
[Abstract] [Full Text] [PDF]


Home page
JAMAHome page
E. Fox, K. Landrum-McNiff, Z. Zhong, N. V. Dawson, A. W. Wu, J. Lynn, and for the SUPPORT Investigators
Evaluation of Prognostic Criteria for Determining Hospice Eligibility in Patients With Advanced Lung, Heart, or Liver Disease
JAMA, November 3, 1999; 282(17): 1638 - 1645.
[Abstract] [Full Text] [PDF]


Home page
CMAJHome page
J. F. Seely and B. M. Mount
Palliative medicine and modern technology
Can. Med. Assoc. J., November 1, 1999; 161(9): 1120 - 1121.
[Full Text] [PDF]


Home page
ANN INTERN MEDHome page
E. W. Ely, G. W. Evans, and E. F. Haponik
Mechanical Ventilation in a Cohort of Elderly Patients Admitted to an Intensive Care Unit
Ann Intern Med, July 20, 1999; 131(2): 96 - 104.
[Abstract] [Full Text] [PDF]


Home page
Palliat MedHome page
J. M Teno
Lessons learned and not learned from the SUPPORT project
Palliative Medicine, March 1, 1999; 13(2): 91 - 93.
[PDF]


Home page
ANN INTERN MEDHome page
M. B. Hamel, J. M. Teno, L. Goldman, J. Lynn, R. B. Davis, A. N. Galanos, N. Desbiens, A. F. Connors Jr., N. Wenger, R. S. Phillips, et al.
Patient Age and Decisions To Withhold Life-Sustaining Treatments from Seriously Ill, Hospitalized Adults
Ann Intern Med, January 19, 1999; 130(2): 116 - 125.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
N. A. Christakis and T. J. Iwashyna
Attitude and Self-reported Practice Regarding Prognostication in a National Sample of Internists
Arch Intern Med, November 23, 1998; 158(21): 2389 - 2395.
[Abstract] [Full Text] [PDF]




 Home | Current Issue | Past Issues | In the Clinic | ACP Journal Club | CME | Collections | Audio/Video | Mobile | Subscribe | Tools | Help | ACP Online 

Copyright © 1996 by the American College of Physicians.