Annals
Established in 1927 by the American College of Physicians
:
Advanced search
 
box Article
 arrow  Table of Contents                
space
 arrow  Full Text of this article Free
space
 arrow  Figures/Tables List
space
box Services
 arrow  Send comment/rapid response letter
space
 arrow  Notify a friend about this article
space
 arrow  Alert me when this article is cited
space
 arrow  Add to Personal Archive
space
 arrow  Download to Citation Manager
space
 arrow  ACP Search                        
space
 arrow  Get Permissions
space
box Google Scholar
 arrow  Search for Related Content
space
box PubMed
Articles in PubMed by Author:
  arrow  Olin, J. W.
space
  arrow  Childs, M. B.
space
 arrow  Related Articles in PubMed
space
 arrow  PubMed Citation
space
 arrow  PubMed
space

ARTICLE

The Utility of Duplex Ultrasound Scanning of the Renal Arteries for Diagnosing Significant Renal Artery Stenosis

right arrow Jeffrey W. Olin; Marion R. Piedmonte; Jess R. Young; Susan DeAnna; Michael Grubb; and Mary Beth Childs

1 June 1995 | Volume 122 Issue 11 | Pages 833-838

Objective: To determine the utility of duplex ultrasound scanning of the renal arteries in identifying patients with renal artery stenosis of 60% or more and in excluding patients with either normal renal arteries or renal artery stenosis of less than 60%.

Design: A prospective, blinded study.

Setting: Large tertiary referral center.

Patients: 102 consecutive patients (44 men and 58 women with a mean age [±SD] of 63.3 ±13.4 years) who had both duplex ultrasound scanning of the renal arteries and renal arteriography. All patients who were studied had hypertension that was difficult to control, unexplained azotemia, or associated peripheral vascular disease (alone or in combination), giving them a high pretest likelihood of renovascular disease.

Main Outcome Measurements: Peak systolic and end diastolic velocities, renal-aortic ratios, resistive index, and kidney sizes.

Results: Sixty-two of 63 arteries with stenosis of less than 60% using arteriography were correctly identified by duplex ultrasound scanning. Thirty-one of 32 arteries with 60% to 79% stenosis using arteriography were correctly identified as having 60% to 99% stenosis on duplex ultrasound, whereas 67 of 69 arteries with 80% to 99% stenosis on arteriography were correctly identified as having 60% to 99% stenosis on ultrasound. Twenty-two of 23 arteries with total occlusion on arteriography were correctly identified by duplex ultrasound. The overall sensitivity of duplex ultrasound compared with arteriography was 0.98, the specificity was 0.98, the positive predictive value was 0.99, and the negative predictive value was 0.97.

Conclusion: Duplex ultrasound scanning of the renal arteries is an ideal screening test because it is noninvasive and can predict the presence or absence of renal artery stenosis with a high degree of accuracy.

Author and Article Information
space

From Cleveland Clinic Foundation, Cleveland, Ohio.
Requests for Reprints: Jeffrey W. Olin, DO, Department of Vascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195.
Acknowledgments: The authors thank Micheline Watt for her assistance in the preparation of this manuscript.




This article has been cited by other articles:


Home page
Eur Heart JHome page
B. Drieghe, J. Madaric, G. Sarno, G. Manoharan, J. Bartunek, G. R. Heyndrickx, N. H.J. Pijls, and B. De Bruyne
Assessment of renal artery stenosis: side-by-side comparison of angiography and duplex ultrasound with pressure gradient measurements
Eur. Heart J., February 2, 2008; 29(4): 517 - 524.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Roentgenol.Home page
G. J. Williams, P. Macaskill, S. F. Chan, T. E. Karplus, W. Yung, E. M. Hodson, and J. C. Craig
Comparative Accuracy of Renal Duplex Sonographic Parameters in the Diagnosis of Renal Artery Stenosis: Paired and Unpaired Analysis
Am. J. Roentgenol., March 1, 2007; 188(3): 798 - 811.
[Abstract] [Full Text] [PDF]


Home page
RadiologyHome page
S. Willoteaux, M. Faivre-Pierret, O. Moranne, C. Lions, J. Bruzzi, M. Finot, V. Gaxotte, C. Mounier-Vehier, and J.-P. Beregi
Fibromuscular Dysplasia of the Main Renal Arteries: Comparison of Contrast-enhanced MR Angiography with Digital Subtraction Angiography
Radiology, December 1, 2006; 241(3): 922 - 929.
[Abstract] [Full Text] [PDF]


Home page
J Ultrasound MedHome page
J.-C. Li, L. Wang, Y.-X. Jiang, Q. Dai, S. Cai, K. Lv, and Z.-H. Qi
Evaluation of Renal Artery Stenosis With Velocity Parameters of Doppler Sonography
J. Ultrasound Med., June 1, 2006; 25(6): 735 - 742.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
C. J. White
Catheter-Based Therapy for Atherosclerotic Renal Artery Stenosis
Circulation, March 21, 2006; 113(11): 1464 - 1473.
[Full Text] [PDF]


Home page
J Ultrasound MedHome page
G. M. Soares, T. P. Murphy, M. S. Singha, A. Parada, and M. Jaff
Renal artery duplex ultrasonography as a screening and surveillance tool to detect renal artery stenosis: a comparison with current reference standard imaging.
J. Ultrasound Med., March 1, 2006; 25(3): 293 - 298.
[Abstract] [Full Text] [PDF]


Home page
RadioGraphicsHome page
H. Ota, K. Takase, H. Rikimaru, M. Tsuboi, T. Yamada, A. Sato, S. Higano, T. Ishibashi, and S. Takahashi
Quantitative Vascular Measurements in Arterial Occlusive Disease
RadioGraphics, September 1, 2005; 25(5): 1141 - 1158.
[Abstract] [Full Text] [PDF]


Home page
ImagingHome page
C C Geddes and G M Baxter
Renal impairment
Imaging, January 1, 2005; 17(1): 1 - 18.
[Abstract] [Full Text] [PDF]


Home page
PERSPECT VASC SURG ENDOVASC THERHome page
R. E. Zierler
Atherosclerotic Renovascular Disease: Natural History and Diagnosis
Perspectives in Vascular Surgery and Endovascular Therapy, December 1, 2004; 16(4): 299 - 310.
[Abstract] [PDF]


Home page
CirculationHome page
J. W. Olin, J. A. Kaufman, D. A. Bluemke, R. O. Bonow, M. D. Gerhard, M. R. Jaff, G. D. Rubin, and W. Hall
Atherosclerotic Vascular Disease Conference: Writing Group IV: Imaging
Circulation, June 1, 2004; 109(21): 2626 - 2633.
[Full Text] [PDF]


Home page
NEJMHome page
D. P. Slovut and J. W. Olin
Fibromuscular Dysplasia
N. Engl. J. Med., April 29, 2004; 350(18): 1862 - 1871.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
Z. G. Turi and M. R. Jaff
Renal artery stenosis: searching for the algorithms for diagnosis and treatment
J. Am. Coll. Cardiol., April 16, 2003; 41(8): 1312 - 1315.
[Full Text] [PDF]


Home page
Vasc MedHome page
S. Gustavson and J. W Olin
Images in vascular medicine: Clues to severe arterial stenosis by duplex ultrasound
Vascular Medicine, February 1, 2003; 8(1): 59 - 61.
[PDF]


Home page
Vasc MedHome page
B. H Gray, J. W Olin, M. B. Childs, T. M Sullivan, and J M. Bacharach
Clinical benefit of renal artery angioplasty with stenting for the control of recurrent and refractory congestive heart failure
Vascular Medicine, November 1, 2002; 7(4): 275 - 279.
[Abstract] [PDF]


Home page
J. Am. Soc. Nephrol.Home page
P. C. Zucchelli
Hypertension and Atherosclerotic Renal Artery Stenosis: Diagnostic Approach
J. Am. Soc. Nephrol., November 1, 2002; 13(90003): S184 - 186.
[Abstract] [Full Text]


Home page
HypertensionHome page
S. C. Textor
Progressive Hypertension in a Patient With "Incidental" Renal Artery Stenosis
Hypertension, November 1, 2002; 40(5): 595 - 600.
[Full Text] [PDF]


Home page
J Ultrasound MedHome page
E. G. Grant, L. L. Barr, J. Borgstede, G. A.W. Gooding, U. M. Hamper, B. S. Hertzberg, M. Horrow, R. A. Kane, F. Kremkau, J. W. Meilstrup, et al.
AIUM Standard for the Performance of an Ultrasound Examination of the Abdomen or Retroperitoneum
J. Ultrasound Med., October 1, 2002; 21(10): 1182 - 1187.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
S. J. Huot, J. H. Hansson, H. Dey, and J. Concato
Utility of Captopril Renal Scans for Detecting Renal Artery Stenosis
Arch Intern Med, September 23, 2002; 162(17): 1981 - 1984.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. H. Rundback, D. Sacks, K. C. Kent, C. Cooper, D. Jones, T. Murphy, K. Rosenfield, C. White, M. Bettmann, S. Cortell, et al.
Guidelines for the Reporting of Renal Artery Revascularization in Clinical Trials
Circulation, September 17, 2002; 106(12): 1572 - 1585.
[Full Text] [PDF]


Home page
J Ultrasound MedHome page
H.-Y. Lee and E. G. Grant
Sonography in Renovascular Hypertension
J. Ultrasound Med., April 1, 2002; 21(4): 431 - 441.
[Abstract] [Full Text] [PDF]


Home page
Br Med BullHome page
C. J White
Non-surgical treatment of patients with peripheral vascular disease
Br. Med. Bull., October 1, 2001; 59(1): 173 - 192.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
G. B. C. Vasbinder, P. J. Nelemans, A. G.H. Kessels, A. A. Kroon, P. W. de Leeuw, and J. M.A. van Engelshoven
Diagnostic Tests for Renal Artery Stenosis in Patients Suspected of Having Renovascular Hypertension: A Meta-Analysis
Ann Intern Med, September 18, 2001; 135(6): 401 - 411.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Roentgenol.Home page
D. J. Spinosa, A. H. Matsumoto, J. F. Angle, K. D. Hagspiel, D. Cage, E. A. Bissonette, K. G. Koenig, C. R. Ayers, and K. McConnell
Safety of CO2- and Gadodiamide-Enhanced Angiography for the Evaluation and Percutaneous Treatment of Renal Artery Stenosis in Patients with Chronic Renal Insufficiency
Am. J. Roentgenol., May 1, 2001; 176(5): 1305 - 1311.
[Abstract] [Full Text] [PDF]


Home page
RadioGraphicsHome page
S. D. Sarkar, D. N. Siegel, G. Soulez, and V. L. Oliva
Invited Commentary Authors' Response
RadioGraphics, September 1, 2000; 20(5): 1368 - 1372.
[Full Text] [PDF]


Home page
RadiologyHome page
I. Baumgartner, K. von Aesch, D.-D. Do, J. Triller, M. Birrer, and F. Mahler
Stent Placement in Ostial and Nonostial Atherosclerotic Renal Arterial Stenoses: A Prospective Follow-up Study
Radiology, August 1, 2000; 216(2): 498 - 505.
[Abstract] [Full Text]


Home page
Nephrol Dial TransplantHome page
I. Krenz, G. Wolf, and R. A. K. Stahl
Premature closure or do not get lost in your diagnostic work-up and blame it on the patient
Nephrol. Dial. Transplant., July 1, 2000; 15(7): 1072 - 1075.
[Full Text] [PDF]


Home page
RadiologyHome page
M. Claudon, P. F. Plouin, G. M. Baxter, T. Rohban, and D. M. Devos
Renal Arteries in Patients at Risk of Renal Arterial Stenosis: Multicenter Evaluation of the Echo-enhancer SH U 508A at Color and Spectral Doppler US
Radiology, March 1, 2000; 214(3): 739 - 746.
[Abstract] [Full Text]


Home page
RadiologyHome page
F. De Cobelli, M. Venturini, A. Vanzulli, S. Sironi, M. Salvioni, E. Angeli, P. Scifo, M. P. Garancini, R. Quartagno, G. Bianchi, et al.
Renal Arterial Stenosis: Prospective Comparison of Color Doppler US and Breath-hold, Three-dimensional, Dynamic, Gadolinium-enhanced MR Angiography
Radiology, February 1, 2000; 214(2): 373 - 380.
[Abstract] [Full Text]


Home page
RadiologyHome page
R. O. Bude, R. G. Larson, W. W. Nichols, and J. M. Rubin
Stenosis of the Main Artery Supplying an Organ: Effect of End-Organ Vascular Resistance on the Poststenotic Peak Systolic Velocity in an in Vitro Hydraulic Model at Doppler US
Radiology, July 1, 1999; 212(1): 79 - 87.
[Abstract] [Full Text]


Home page
HypertensionHome page
D. A. Leung, U. Hoffmann, T. Pfammatter, T. F. Hany, L. Rainoni, P. Hilfiker, E. Schneider, G. G. Zimmermann-Paul, and J. F. Debatin
Magnetic Resonance Angiography Versus Duplex Sonography for Diagnosing Renovascular Disease
Hypertension, February 1, 1999; 33(2): 726 - 731.
[Abstract] [Full Text] [PDF]


Home page
PERSPECT VASC SURG ENDOVASC THERHome page
R. E. Zierler
Natural History Of Atherosclerotic Renal Artery Stenosis
Perspectives in Vascular Surgery and Endovascular Therapy, January 1, 1999; 11(1): 55 - 67.
[Abstract] [PDF]


Home page
CirculationHome page
M. T. Caps, C. Perissinotto, R. E. Zierler, N. L. Polissar, R. O. Bergelin, M. J. Tullis, K. Cantwell-Gab, R. C. Davidson, and D. E. Strandness Jr
Prospective Study of Atherosclerotic Disease Progression in the Renal Artery
Circulation, December 22, 1998; 98(25): 2866 - 2872.
[Abstract] [Full Text] [PDF]


Home page
ANGIOLOGYHome page
L. S. Malatino, G. Polizzi, M. Garozzo, F. Rapisarda, P. Fatuzzo, I. Bellanuova, A. Cataliotti, A. Brozzetti, S. Neri, P. A. Malfa, et al.
Diagnosis of Renovascular Disease by Extra- and Intrarenal Doppler Parameters
Angiology, October 1, 1998; 49(10): 707 - 721.
[Abstract] [PDF]


Home page
VASC ENDOVASCULAR SURGHome page
R. E. Zierler
Is the "Shrinking" Kidney an Indication for Intervention?
Vascular and Endovascular Surgery, September 1, 1997; 31(5): 515 - 518.
[PDF]


Home page
NEJMHome page
C. T. Postma, T. Thien, U. Blum, and B. Krumme
Treatment of Ostial Renal-Artery Stenoses with Vascular Endoprostheses
N. Engl. J. Med., July 10, 1997; 337(2): 132 - 133.
[Full Text]


Home page
NEJMHome page
U. Blum, B. Krumme, P. Flugel, A. Gabelmann, T. Lehnert, C. Buitrago-Tellez, P. Schollmeyer, and M. Langer
Treatment of Ostial Renal-Artery Stenoses with Vascular Endoprostheses after Unsuccessful Balloon Angioplasty
N. Engl. J. Med., February 13, 1997; 336(7): 459 - 465.
[Abstract] [Full Text] [PDF]


Home page
JWatch GeneralHome page
DUPLEX ULTRASOUND FOR RENAL ARTERY STENOSIS
Journal Watch (General), June 13, 1995; 1995(613): 1 - 1.
[Full Text]


Home page
RadiologyHome page
M. C. Dumars, W. E. Thompson, E. I. Bluth, J. S. Lindberg, M. Yoselevitz, and C. R. B. Merritt
Management of Suspected Hemodialysis Graft Dysfunction: Usefulness of Diagnostic US
Radiology, January 1, 2002; 222(1): 103 - 107.
[Abstract] [Full Text] [PDF]




 Home | Current Issue | Past Issues | In the Clinic | ACP Journal Club | CME | Collections | Audio/Video | Mobile | Subscribe | Tools | Help | ACP Online 

Copyright © 1995 by the American College of Physicians.