| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 December 1994 | Volume 121 Issue 11 | Pages 866-872
Objective: To study the relation between housestaff coverage schedules and the occurrence of preventable adverse events.
Design: Case-control study.
Setting: Urban teaching hospital.
Patients: All 3146 patients admitted to the medical service during a 4-month period.
Measurements: A previously tested confidential self-report system to identify adverse events, which were defined as unexpected complications of medical therapy that resulted in increased length of stay or disability at discharge. A panel of three board-certified internists confirmed events and evaluated preventability based on case summaries. Housestaff coverage was coded according to the day in the usual intern's schedule and to cross-coverage status. Cross-coverage was defined as care by a house officer who was not the patient's usual intern and not a member of the usual intern's patient care team. Coverage for an adverse event was assigned according to who was covering during the proximate cause of that event. Clinical data were collected for each patient and two matched controls.
Results: Of the 124 adverse events reported and confirmed, 54 (44%) were judged potentially preventable. In the univariate analysis, patients with potentially preventable adverse events were more likely than their controls to be covered by a physician from another team at the time of the event (26% compared with 12% [odds ratio, 3.5; P = 0.01]). In the multivariate analysis, three factors were significant independent correlates of potentially preventable adverse events: cross-coverage (odds ratio, 6.1; 95% CI, 1.4 to 26.7), Acute Physiology and Chronic Health Evaluation II score (odds ratio per point, 1.2; CI, 1.1 to 1.4), and history of gastrointestinal bleeding (odds ratio, 4.7; CI, 1.2 to 19.0).
Conclusion: Potentially preventable adverse events were strongly associated with coverage by a physician from another team, which may reflect management by housestaff unfamiliar with the patient. The results emphasize the need for careful attention to the outcome of work-hour reforms for housestaff.
Author and Article Information
From Brigham and Women's Hospital, Harvard Medical School, and Harvard University School of Public Health, Boston, Massachusetts.
ACADEMIA AND CLINIC
Does Housestaff Discontinuity of Care Increase the Risk for Preventable Adverse Events?
![]()
Requests for Reprints: Thomas H. Lee, MD, Section for Clinical Epidemiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115.
Acknowledgments: The authors thank Drs. Eugene Braunwald, Lee Goldman, Howard H. Hiatt, Anthony L. Komaroff, H. Richard Nesson, George E. Thibault, and Marshall A. Wolf for their advice, support, and thoughtful reviews of this manuscript; Dr. David W. Bates for his assistance; and the members of the Brigham and Women's Hospital medical housestaff.
Grant Support: In part by the Aso-Nesson Research Institute and a grant from the Julian and Eunice Cohen Educational Fund at Brigham and Women's Hospital. Dr. Lee is the recipient of an Established Investigator Award[900119] from the American Heart Association.
This article has been cited by other articles:
![]() |
C. P. Landrigan, A. M. Fahrenkopf, D. Lewin, P. J. Sharek, L. K. Barger, M. Eisner, S. Edwards, V. W. Chiang, B. L. Wiedermann, and T. C. Sectish Effects of the Accreditation Council for Graduate Medical Education Duty Hour Limits on Sleep, Work Hours, and Safety Pediatrics, August 1, 2008; 122(2): 250 - 258. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. C. Watson Crossroads: Two Points of View: RESIDENT WORK HOURS: DISTINGUISHING RESIDENT SERVICE ISSUES FROM EDUCATION AND SAFETY Neurology, July 29, 2008; 71(5): 375 - 376. [Full Text] [PDF] |
||||
![]() |
W. Dunn and J. G. Murphy The Patient Handoff: Medicine's Formula One Moment Chest, July 1, 2008; 134(1): 9 - 12. [Full Text] [PDF] |
||||
![]() |
R. Kaushal, D. W. Bates, E. L. Abramson, J. R. Soukup, and D. A. Goldmann Unit-based clinical pharmacists' prevention of serious medication errors in pediatric inpatients Am. J. Health Syst. Pharm., July 1, 2008; 65(13): 1254 - 1260. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Bartlett PhD, R. Blais PhD, R. Tamblyn PhD, R. J. Clermont MD, and B. MacGibbon PhD Impact of patient communication problems on the risk of preventable adverse events in acute care settings Can. Med. Assoc. J., June 3, 2008; 178(12): 1555 - 1562. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. G. Volpp A Delicate Balance: Physician Work Hours, Patient Safety, and Organizational Efficiency Circulation, May 20, 2008; 117(20): 2580 - 2582. [Full Text] [PDF] |
||||
![]() |
J. L. Schuberth, T. A. Elasy, J. Butler, R. Greevy, T. Speroff, R. S. Dittus, and C. L. Roumie Effect of Short Call Admission on Length of Stay and Quality of Care for Acute Decompensated Heart Failure Circulation, May 20, 2008; 117(20): 2637 - 2644. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. C. Fonarow, W. T. Abraham, N. M. Albert, W. Gattis Stough, M. Gheorghiade, B. H. Greenberg, C. M. O'Connor, E. Nunez, C. W. Yancy, and J. B. Young Day of Admission and Clinical Outcomes for Patients Hospitalized for Heart Failure: Findings From the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF) Circ Heart Fail, May 1, 2008; 1(1): 50 - 57. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Jagsi, D. F. Weinstein, J. Shapiro, B. T. Kitch, D. Dorer, and J. S. Weissman The Accreditation Council for Graduate Medical Education's Limits on Residents' Work Hours and Patient Safety: A Study of Resident Experiences and Perceptions Before and After Hours Reductions Arch Intern Med, March 10, 2008; 168(5): 493 - 500. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Rasminsky, A. Lomonaco, and E. Auchincloss Work Hours Regulations for House Staff in Psychiatry: Bad or Good for Residency Training? Acad Psychiatry, February 1, 2008; 32(1): 54 - 60. [Abstract] [Full Text] [PDF] |
||||
![]() |
D P Stevens Handovers and Debussy Qual. Saf. Health Care, February 1, 2008; 17(1): 2 - 3. [Full Text] [PDF] |
||||
![]() |
V M Arora, J K Johnson, D O Meltzer, and H J Humphrey A theoretical framework and competency-based approach to improving handoffs Qual. Saf. Health Care, February 1, 2008; 17(1): 11 - 14. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Frost and M. Wise Residency Duty-Hour Limits: Time to Change How Key Clinical Faculty Work? Arch Intern Med, January 28, 2008; 168(2): 244 - 244. [Full Text] [PDF] |
||||
![]() |
H. Singh, S. Sethi, M. Raber, and L. A. Petersen Errors in Cancer Diagnosis: Current Understanding and Future Directions J. Clin. Oncol., November 1, 2007; 25(31): 5009 - 5018. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Singh, E. J. Thomas, L. A. Petersen, and D. M. Studdert Medical Errors Involving Trainees: A Study of Closed Malpractice Claims From 5 Insurers Arch Intern Med, October 22, 2007; 167(19): 2030 - 2036. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. G. Volpp, A. K. Rosen, P. R. Rosenbaum, P. S. Romano, O. Even-Shoshan, Y. Wang, L. Bellini, T. Behringer, and J. H. Silber Mortality Among Hospitalized Medicare Beneficiaries in the First 2 Years Following ACGME Resident Duty Hour Reform JAMA, September 5, 2007; 298(9): 975 - 983. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. G. Volpp, A. K. Rosen, P. R. Rosenbaum, P. S. Romano, O. Even-Shoshan, A. Canamucio, L. Bellini, T. Behringer, and J. H. Silber Mortality Among Patients in VA Hospitals in the First 2 Years Following ACGME Resident Duty Hour Reform JAMA, September 5, 2007; 298(9): 984 - 992. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. K. Lighthall and J. Barr The Use of Clinical Simulation Systems to Train Critical Care Physicians J Intensive Care Med, September 1, 2007; 22(5): 257 - 269. [Abstract] [PDF] |
||||
![]() |
D. Leff, O. Aziz, and A. Darzi Trucks, Planes, and Scalpels: Is There an Evidence-Based Approach to Surgeons' Working Hours? Arch Surg, September 1, 2007; 142(9): 817 - 820. [Full Text] [PDF] |
||||
![]() |
C. M. Bell MD PhD and J. G. Ray MD MSc "You're not my obstetrician" (and it may not matter) Can. Med. Assoc. J., August 14, 2007; 177(4): 372 - 373. [Full Text] [PDF] |
||||
![]() |
A. Salim, P. G. R. Teixeira, L. Chan, D. Oncel, K. Inaba, C. Brown, P. Rhee, and T. V. Berne Impact of the 80-Hour Workweek on Patient Care at a Level I Trauma Center Arch Surg, August 1, 2007; 142(8): 708 - 714. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. I. Horwitz, M. Kosiborod, Z. Lin, and H. M. Krumholz Changes in Outcomes for Internal Medicine Inpatients after Work-Hour Regulations Ann Intern Med, July 17, 2007; 147(2): 97 - 103. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Okie An Elusive Balance -- Residents' Work Hours and the Continuity of Care N. Engl. J. Med., June 28, 2007; 356(26): 2665 - 2667. [Full Text] [PDF] |
||||
![]() |
M. Ong, A. Bostrom, A. Vidyarthi, C. McCulloch, and A. Auerbach House Staff Team Workload and Organization Effects on Patient Outcomes in an Academic General Internal Medicine Inpatient Service Arch Intern Med, January 8, 2007; 167(1): 47 - 52. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. M. Bell, J. Bajcar, A. S. Bierman, P. Li, M. M. Mamdani, and D. R. Urbach Potentially Unintended Discontinuation of Long-term Medication Use After Elective Surgical Procedures Arch Intern Med, December 11, 2006; 166(22): 2525 - 2531. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. R. Keenan, H. H. Nguyen, and M. Srinivasan Electronic Medical Records and Their Impact on Resident and Medical Student Education Acad Psychiatry, December 1, 2006; 30(6): 522 - 527. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. G. Shojania, K. E. Fletcher, and S. Saint Graduate medical education and patient safety: a busy--and occasionally hazardous--intersection. Ann Intern Med, October 17, 2006; 145(8): 592 - 598. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. P. Landrigan, L. K. Barger, B. E. Cade, N. T. Ayas, and C. A. Czeisler Interns' compliance with accreditation council for graduate medical education work-hour limits. JAMA, September 6, 2006; 296(9): 1063 - 1070. [Abstract] [Full Text] [PDF] |
||||
![]() |
M C Wright, B Phillips-Bute, J B Mark, M Stafford-Smith, K P Grichnik, B C Andregg, and J M Taekman Time of day effects on the incidence of anesthetic adverse events. Qual. Saf. Health Care, August 1, 2006; 15(4): 258 - 263. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. I. Horwitz, H. M. Krumholz, M. L. Green, and S. J. Huot Transfers of patient care between house staff on internal medicine wards: a national survey. Arch Intern Med, June 12, 2006; 166(11): 1173 - 1177. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. Arora, C. Dunphy, V. Y. Chang, F. Ahmad, H. J. Humphrey, and D. Meltzer The effects of on-duty napping on intern sleep time and fatigue. Ann Intern Med, June 6, 2006; 144(11): 792 - 798. [Abstract] [Full Text] [PDF] |
||||
![]() |
H Singh, L A Petersen, and E J Thomas Understanding diagnostic errors in medicine: a lesson from aviation. Qual. Saf. Health Care, June 1, 2006; 15(3): 159 - 164. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Goitein, T. D. Shanafelt, J. E. Wipf, C. G. Slatore, and A. L. Back The Effects of Work-Hour Limitations on Resident Well-being, Patient Care, and Education in an Internal Medicine Residency Program Arch Intern Med, December 12, 2005; 165(22): 2601 - 2606. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Jagsi, B. T. Kitch, D. F. Weinstein, E. G. Campbell, M. Hutter, and J. S. Weissman Residents Report on Adverse Events and Their Causes Arch Intern Med, December 12, 2005; 165(22): 2607 - 2613. [Abstract] [Full Text] [PDF] |
||||
![]() |
V Arora, J Johnson, D Lovinger, H J Humphrey, and D O Meltzer Communication failures in patient sign-out and suggestions for improvement: a critical incident analysis Qual. Saf. Health Care, December 1, 2005; 14(6): 401 - 407. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. A. Feddock, A. R. Hoellein, C. H. Griffith, J. F. Wilson, N. S. Becker, J. L. Bowerman, and T. S. Caudill Are Continuity Clinic Patients Less Satisfied When Residents Have a Heavy Inpatient Workload? Eval Health Prof, December 1, 2005; 28(4): 390 - 399. [Abstract] [PDF] |
||||
![]() |
B. Afessa, C. C. Kennedy, K. W. Klarich, T. R. Aksamit, J. C. Kolars, and R. D. Hubmayr Introduction of a 14-Hour Work Shift Model for Housestaff in the Medical ICU Chest, December 1, 2005; 128(6): 3910 - 3915. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Horsky, G. J. Kuperman, and V. L. Patel Comprehensive Analysis of a Medication Dosing Error Related to CPOE J. Am. Med. Inform. Assoc., July 1, 2005; 12(4): 377 - 382. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Garland Improving the ICU: Part 2 Chest, June 1, 2005; 127(6): 2165 - 2179. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. D. Zuckerman, E. N. Kubiak, I. Immerman, and P. DiCesare The Early Effects of Code 405 Work Rules on Attitudes of Orthopaedic Residents and Attending Surgeons J. Bone Joint Surg. Am., April 1, 2005; 87(4): 903 - 908. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Koppel, J. P. Metlay, A. Cohen, B. Abaluck, A. R. Localio, S. E. Kimmel, and B. L. Strom Role of Computerized Physician Order Entry Systems in Facilitating Medication Errors JAMA, March 9, 2005; 293(10): 1197 - 1203. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. W. Saultz and J. Lochner Interpersonal Continuity of Care and Care Outcomes: A Critical Review Ann. Fam. Med, March 1, 2005; 3(2): 159 - 166. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. K. Gandhi Fumbled Handoffs: One Dropped Ball after Another Ann Intern Med, March 1, 2005; 142(5): 352 - 358. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. E. Fletcher, S. Q. Davis, W. Underwood, R. S. Mangrulkar, L. F. McMahon Jr., and S. Saint Systematic Review: Effects of Resident Work Hours on Patient Safety Ann Intern Med, December 7, 2004; 141(11): 851 - 857. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. W. Mold, G. E. Fryer, and A. M. Roberts When Do Older Patients Change Primary Care Physicians? J Am Board Fam Med, November 1, 2004; 17(6): 453 - 460. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Mukherjee A Precarious Exchange N. Engl. J. Med., October 28, 2004; 351(18): 1822 - 1824. [Full Text] [PDF] |
||||
![]() |
C. P. Landrigan, J. M. Rothschild, J. W. Cronin, R. Kaushal, E. Burdick, J. T. Katz, C. M. Lilly, P. H. Stone, S. W. Lockley, D. W. Bates, et al. Effect of Reducing Interns' Work Hours on Serious Medical Errors in Intensive Care Units N. Engl. J. Med., October 28, 2004; 351(18): 1838 - 1848. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. S. Parshuram Preparing physicians for the real world Can. Med. Assoc. J., September 28, 2004; 171(7): 709 - 709. [Full Text] [PDF] |
||||
![]() |
M. Charap Reducing Resident Work Hours: Unproven Assumptions and Unforeseen Outcomes Ann Intern Med, May 18, 2004; 140(10): 814 - 815. [Full Text] [PDF] |
||||
![]() |
K. M. Skeff, S. Ezeji-Okoye, P. Pompei, and S. Rockson Benefits of Resident Work Hours Regulation Ann Intern Med, May 18, 2004; 140(10): 816 - 817. [Full Text] [PDF] |
||||
![]() |
J. L. Bailit and M. H. Blanchard The Effect of House Staff Working Hours on the Quality of Obstetric and Gynecologic Care Obstet. Gynecol., April 1, 2004; 103(4): 613 - 616. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. A. Rastegar Health Care Becomes an Industry Ann. Fam. Med, January 1, 2004; 2(1): 79 - 83. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. Goldman and A. J. Kirtane Triage of Patients with Acute Chest Pain and Possible Cardiac Ischemia: The Elusive Search for Diagnostic Perfection Ann Intern Med, December 16, 2003; 139(12): 987 - 995. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. W. Saultz Defining and Measuring Interpersonal Continuity of Care Ann. Fam. Med, September 1, 2003; 1(3): 134 - 143. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Tsilimingras, A. K. Rosen, and D. R. Berlowitz Review Article: Patient Safety in Geriatrics: A Call for Action J. Gerontol. A Biol. Sci. Med. Sci., September 1, 2003; 58(9): M813 - 819. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. W. Bates and A. A. Gawande Improving Safety with Information Technology N. Engl. J. Med., June 19, 2003; 348(25): 2526 - 2534. [Full Text] [PDF] |
||||
![]() |
T. A. Brennan and M. J. Zinner Residents' work hours: a wake up call? Int. J. Qual. Health Care, March 1, 2003; 15(2): 107 - 108. [Full Text] [PDF] |
||||
![]() |
J. P. T. Co, T. G. Ferris, B. L. Marino, C. J. Homer, and J. M. Perrin Are Hospital Characteristics Associated With Parental Views of Pediatric Inpatient Care Quality? Pediatrics, February 1, 2003; 111(2): 308 - 314. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. M. Gaba and S. K. Howard Fatigue among Clinicians and the Safety of Patients N. Engl. J. Med., October 17, 2002; 347(16): 1249 - 1255. [Full Text] [PDF] |
||||
![]() |
D. F. Weinstein Duty Hours for Resident Physicians -- Tough Choices for Teaching Hospitals N. Engl. J. Med., October 17, 2002; 347(16): 1275 - 1278. [Full Text] [PDF] |
||||