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1 October 1993 | Volume 119 Issue 7 Part 2 | Pages 688-693
Recent studies of the treatment of obesity by moderate and severe caloric restriction show that patients treated in randomized trials using a conventional 1200 kcal/d reducing diet, combined with behavior modification, lose approximately 8.5 kg in 20 weeks. They maintain approximately two thirds of this weight loss 1 year later. Patients treated under medical supervision using a very-low-calorie diet (400 to 800 kcal/d) lose approximately 20 kg in 12 to 16 weeks and maintain one half to two thirds of this loss in the following year. Both dietary interventions are associated with increasing weight regain over time, although regain can be minimized with the recognition that obesity, in many cases, is a chronic condition that requires continuing care. Patients who participate in a formal weight-loss maintenance program, exercise regularly, or both are likely to achieve the best long-term results.
Author and Article Information
From Syracuse University, Syracuse, New York.
METHODS FOR VOLUNTARY WEIGHT LOSS AND CONTROL: NATIONAL INSTITUTES OF HEALTH TECHNOLOGY ASSESSMENT CONFERENCE
Treatment of Obesity by Moderate and Severe Caloric Restriction: Results of Clinical Research Trials
Requests for Reprints: Thomas A. Wadden, PhD, Center for Health and Behavior, Syracuse University, 804 University Avenue, Syracuse, NY 13244.
Grant Support: By a Research Scientist Development Award (MH00 702-05) from the National Institute of Mental Health (NIMH) and by grant RO1-MH49451-01 from the NIMH.
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