Figure 1. Clinical findings in adults with nephropathic cystinosis not treated with oral cysteamine. A. Short stature and generalized muscle wasting are evident in a 39-year-old man with cystinosis. B. Marked atrophy of the interosseous muscles of the hands is seen in the same patient. C. Electron microscopy of a postmortem specimen revealed shard-like crystals in the cornea of a 22-year-old patient.