Ann Intern Med -- Shojania et al. 0 (2007): 0000605-200708210-00179 Figure A3

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Appendix Figure 3. Kaplan–Meier plot showing the effect on survival of increasing the total number of patients by more than a factor of 2. ${webonly}$

Ratio of new total sample size to old total sample size is >2, which occurred for 25% of systematic reviews in the cohort.